Protein Alignment Efhc1.1 and Efhc1.2

DIOPT Version :10

• Sequence 1: NP_573075.1
• Gene: Efhc1.1 / 32528
• FlyBaseID: FBgn0030691
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: XP_558349.5
• Gene: Efhc1.2 / 1275015
• VectorBaseID: AGAMI1_013705
• Length: 762
• Species: Anopheles gambiae
• Alignment Length: 761
• Identity: 330/761 - (43%)
• Similarity: 491/761 - (64%)
• Gaps: 12/761 - (1%)

  Fly     1 MLRIPGMPLLPGTLFRDVSKGHYPKPQSLANVQGLSMLSDRQQPAPVESGSVTVDISCPPVGASS 65
            |||..|:|.|||..|:|:.:..:.|.........:.:|.|.::|.  ..|...:....|.....|
Mosquito     1 MLRCSGLPFLPGNTFQDIGRSKFHKSHHFDQRNQVCILVDAKRPG--IGGKPLLATDSPEYTLPS 63

  Fly    66 IYPPRSGPRMPPWLAYDKKVLCFHAYFKQTLQEVYHAPYLVRKVKIYYYLEDGTLEIYEPRVDNS 130
            :|||..||..|.||.||::||||:.||:::|..|...||.:|.|:|.|||||.|:::.|||..||
Mosquito    64 LYPPSYGPSRPGWLEYDRQVLCFYGYFQESLGNVDRIPYQIRNVRILYYLEDDTMQVSEPRTLNS 128

  Fly   131 GIVQGCVVHRQRVQKAPPCDNEFMSLIDLNVDQTVQIFDRQYHITDCDPFTRTFLNKRGITVPDP 195
            ||.|||:|.|||:.:.||.|:||.||:|||::.|||:|||.|.||.||.|:|.|||:.|:.||..
Mosquito   129 GIPQGCLVTRQRIPRPPPYDSEFTSLLDLNINHTVQLFDRVYTITGCDDFSRRFLNRLGVAVPGA 193

  Fly   196 VKSPCDPTEEQRKRENQPRSGNLIP--KNHPFAQFLKYDRQILKFQAYWDDR-TEFGDVRKLELC 257
            |:.|.||..|.|::::..:.... |  |.....:||:|||::|:|:..|||| :.||||.:||:.
Mosquito   194 VEQPRDPATELRQQQDSAKMARR-PAYKIDTLGKFLQYDRKVLRFKGVWDDRGSVFGDVHELEVL 257

  Fly   258 YYLSDDTIEIKEQHIRNSGRDGPTVFLKRGRLAREFEGLQLPGQMTPMTLLNVLGTNMRNVRYCV 322
            |:|||||.||||:...|||||...:||:||||.:.|:.|...|..||:|:|||:|..::..||..
Mosquito   258 YHLSDDTFEIKEKLPVNSGRDSNGMFLRRGRLPKTFDHLPAMGASTPVTVLNVVGGGLKGGRYLN 322

  Fly   323 DPLNTGNKEIHYYREKDLQIGSVINVYGRAVVITELDPFTQNYYRQRYGIQDFTPL---PIPARS 384
            |.:..|..:.:|||:.||:||:.:|||||.|::|..|.||::|||:.||::|||||   ..| |.
Mosquito   323 DSVGIGKADGNYYRDADLRIGARLNVYGRMVLLTGCDQFTESYYRESYGLEDFTPLYGYSAP-RE 386

  Fly   385 DDCADHRSERQLPPYNGWGSYEDSVGNCISVEPKPPKSDFKKFIKYDRYVLRFGAKMLSTIKANC 449
            ...|..|:||:|||:||||::|||.|||:::||||||.:|:||:.|||..|||||:|:|.|:.|.
Mosquito   387 QFVAGRRTERELPPFNGWGTHEDSEGNCLTLEPKPPKINFRKFVVYDRCSLRFGARMVSKIQENN 451

  Fly   450 ERIFVISYYLCDDTLQIQEIAVRNSGFLGGEFMKRTRLELPGQERFSCKQPQYYMPWNFFVGSTM 514
            :|.|||||||.|||:.:.||.:||||||||||:||.:|.||.|:.::.::|..|.|.:|::|:|:
Mosquito   452 DRFFVISYYLSDDTISVYEIPIRNSGFLGGEFIKRRKLALPQQDPYAAERPACYGPQHFYLGATV 516

  Fly   515 SLKDFIFHIVSADEYTLMYMEHHPEIFPHANVGVIMEKVKSALQNRMAEFVGSCVPDCTD--LEK 577
            .|:|..|||.:||.|.|.:||.|.|.||.:|:|.|:.|::.|:|.:..|:|...:.....  ::.
Mosquito   517 RLQDHQFHITNADIYALRFMEQHCEEFPLSNLGKIVRKLRDAMQPQYKEYVAKHMAKIAQVKIDG 581

  Fly   578 KRDVFVSFESFKGALISIMGNQISDHEIISLCRHFSAEKSQPNACDRSTVRAAAHLELKRTLWNA 642
            :....:::|:.:..||.::|.:|.|.||::|||.||||..||..|||..||:|.|.||.|.||:.
Mosquito   582 RTVSTITYEALREILIELLGERIVDQEIVTLCRLFSAESEQPEPCDRELVRSAVHAELNRALWSD 646

  Fly   643 RDDLMEHFHHINPTNQPFLPEVKVRSALRGCRLPFSLELIDNILSILNRNECDDIEVCDLMNFID 707
            .:...||.:|:.||...:|...::|:.::.|::|....|:|.:|.:||:|...:|.:.|.:..::
Mosquito   647 LERTKEHIYHLEPTGAEWLTPQRIRTIVKACKIPLDCALVDKMLQVLNKNGEGNISMEDFLTMLN 711

  Fly   708 VSCGKGCDMLPVNHAFELCPKIPFLNKGRVVNFTCFLRELNLPLNL 753
            .:......:.|:|...::|...|:...|::||:...|..::|...|
Mosquito   712 PAAVPSKPIQPLNIKHDVCHFTPYRVTGKLVNWDELLAHIDLERTL 757

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Efhc1.1	NP_573075.1	DM10	82..189	CDD:128921	60/106 (57%)
		DM10	232..370	CDD:128921	69/138 (50%)
		DM10_dom	424..530	CDD:461948	57/105 (54%)
Efhc1.2	XP_558349.5	None