| Sequence 1: | NP_573075.1 | Gene: | Efhc1.1 / 32528 | FlyBaseID: | FBgn0030691 | Length: | 793 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_060570.2 | Gene: | EFHC1 / 114327 | HGNCID: | 16406 | Length: | 640 | Species: | Homo sapiens |
| Alignment Length: | 615 | Identity: | 207/615 - (33%) |
|---|---|---|---|
| Similarity: | 316/615 - (51%) | Gaps: | 62/615 - (10%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 4 IPGMPLLPGTLFRDVSKGHYPKPQSLANVQGLSML--------SDRQQPAPVESGSVTVDISCPP 60
Fly 61 V---GASSIYPPRSGPRMPPWLAYDKKVLCFHAYFKQTLQEVYHAPYLVRKVKIYYYLEDGTLEI 122
Fly 123 YEPRVDNSGIVQGCVVHRQRVQKAPPCDNEFMSLIDLNVDQTVQIFDRQYHITDCDPFTRTFLNK 187
Fly 188 RGITVPDPVKSPCDPTEEQRKRENQPRSGNLIPKN-HPFAQFLKYDRQILKFQAYWDDR-TEFGD 250
Fly 251 VRKLELCYYLSDDTIEIKEQHIRNSGRDGPTVFLKRGRLAREFEGLQLPGQMTPMTLLNVLGTNM 315
Fly 316 RNVRYCVDPLNTGNKEI-HYYREKDLQIGSVINVYGRAVVITELDPFTQNYYRQRYGIQDFTPLP 379
Fly 380 IPARSDDCADHRSERQLPPYNGWGSYEDSVGNCISVEPKPPKSDFKKFIKYDRYVLRFGAKMLST 444
Fly 445 IKANCERIFVISYYLCDDTLQIQEIAVRNSGFLGGEFMKRTRLELPGQERFSCKQPQYYMPWNFF 509
Fly 510 VGSTMSLKDFIFHIVSADEYTLMYMEHHPEIFPHANVGVIMEKVKSALQNRMAEFVGSCVPDCTD 574
Fly 575 LEKKRDVFV-SFESFKGALISIMGNQISDH 603 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Efhc1.1 | NP_573075.1 | DM10 | 82..189 | CDD:128921 | 44/106 (42%) |
| DUF1126 | 110..142 | CDD:284078 | 17/31 (55%) | ||
| DM10 | 232..370 | CDD:128921 | 48/139 (35%) | ||
| DUF1126 | 256..288 | CDD:284078 | 16/31 (52%) | ||
| DM10 | 431..538 | CDD:128921 | 42/106 (40%) | ||
| DUF1126 | 454..486 | CDD:284078 | 15/31 (48%) | ||
| EFHC1 | NP_060570.2 | Required for its localization in the mitotic spindle and interaction with alpha-tubulin. /evidence=ECO:0000269|PubMed:19734894 | 1..45 | 12/38 (32%) | |
| DM10 | 93..198 | CDD:128921 | 44/106 (42%) | ||
| DUF1126 | 122..153 | CDD:284078 | 17/30 (57%) | ||
| DM10 | 239..359 | CDD:128921 | 48/139 (35%) | ||
| DUF1126 | 263..296 | CDD:284078 | 16/32 (50%) | ||
| DM10 | 416..520 | CDD:128921 | 42/114 (37%) | ||
| DUF1126 | 439..471 | CDD:284078 | 15/31 (48%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 535..554 | 1/19 (5%) | |||
| EFh | 579..639 | CDD:238008 | |||
| EF-hand_7 | 579..638 | CDD:290234 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 82 | 1.000 | Domainoid score | I8413 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG0043 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 1 | 1.010 | - | - | QHG56477 | |
| OrthoDB | 1 | 1.010 | - | - | D126718at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0002682 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_101134 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 8 | 7.730 | |||||