Protein Alignment Efhc1.1 and efhc2

DIOPT Version :10

• Sequence 1: NP_573075.1
• Gene: Efhc1.1 / 32528
• FlyBaseID: FBgn0030691
• Length: 793
• Species: Drosophila melanogaster
• Sequence 2: NP_001136133.1
• Gene: efhc2 / 100126059
• XenbaseID: XB-GENE-960325
• Length: 741
• Species: Xenopus tropicalis
• Alignment Length: 729
• Identity: 253/729 - (34%)
• Similarity: 407/729 - (55%)
• Gaps: 62/729 - (8%)

  Fly     7 MPLLPGTLF-RDVSKGHYPKPQSLANVQGLSMLSDRQQPAPVESGSVTVDISCPPVGASSIYPPR 70
            :|.|||..| |::.|..:.|.|.......:||....::|.  ..|:..:..:..|  ..|::|..
 Frog     3 LPFLPGNSFNRNLGKEKFHKSQHFGYSNDISMWLGEEKPG--VGGAPLLGQNLKP--KFSVFPKG 63

  Fly    71 SGPRMPPWLAYDKKVLCFHAYFKQTLQEVYHAPYLVRKVKIYYYLEDGTLEIYEPRVDNSGIVQG 135
            .|...|.|:|:||:||.|.|||::.:.:.....|.:|:.|||:||||.|:::.||.:.||||.||
 Frog    64 VGSDAPSWVAFDKQVLSFDAYFEEEVHQRREETYRIRQCKIYFYLEDDTIQVVEPEIKNSGIPQG 128

  Fly   136 CVVHRQRVQKAPPCDNEFMSLIDLNVDQTVQIFDRQYHITDCDPFTRTFLNKRGITVPDPVKSPC 200
            .::.|.|:....|.|::|.::..||:::.:..:.:.|.|.:||.|||.||.|.|:.:..|...|.
 Frog   129 TIIRRHRIPLPAPNDDQFYTVDHLNLNKDIVFYSKIYRIVNCDEFTRNFLRKLGVRINPPDSVPS 193

  Fly   201 DPTEEQRKR--ENQPRSGNLIP--KNHPFAQFLKYDRQILKFQAYWDDRTEFGDVRKLELCYYLS 261
            |.....||:  |.||    |.|  :.....|||::||.:|:|..:|||.|.|||.|:|.|.|||:
 Frog   194 DAYSSTRKKMEEMQP----LRPYERIDTLKQFLEHDRHVLRFFCFWDDTTLFGDSRELVLYYYLA 254

  Fly   262 DDTIEIKEQHIRNSGRDGPTVFLKRGRLAREF-EGLQLPGQMTPMTLLNVLGTNMRNVRYCVDPL 325
            |||:||.|....|||||...|||.||:|.:.. :.:..|||:|..|:|||.|......||.:|.|
 Frog   255 DDTVEILEIIPANSGRDTTPVFLHRGKLPKSSPQNVPQPGQVTARTVLNVFGPMGHGGRYILDNL 319

  Fly   326 NTGNKEIHYYREKDLQIGSVINVYGRAVVITELDPFTQNYYRQRYGIQDFTPLPIPARSDDCADH 390
            .||.....:|::.||.||:.:||:||.|::.:.|.||:|||:.::||:||||:...|....
 Frog   320 KTGAVHEEFYKDSDLTIGAALNVWGRKVILCDCDEFTKNYYKTKFGIEDFTPVQYKAPQPP---- 380

  Fly   391 RSERQLPPYNGWGSYEDSVGNCISVEPKPPKSDFKKFIKYDR-----YVLRFGAKMLSTIKANCE 450
            |.:::.|||||:||..|::.:|:::.||||:.|||||::.||     .||||.|::.:....:.|
 Frog   381 RPKKEFPPYNGFGSEADTLCSCMALLPKPPQRDFKKFMEKDRNGLESNVLRFVARLDTDNPIDKE 445

  Fly   451 RIFVISYYLCDDTLQIQEIAVRNSGFLGGEFMKRTRLELPGQERFSCKQPQYYMPWNFFVGSTMS 515
            |.|::||:|.|||:.:.|...||||.:||:|::|:|::.|||:.|..:..:|:.|.:.|||:.::
 Frog   446 RKFIVSYFLSDDTVTVFEPQERNSGMVGGKFLERSRVKKPGQQLFKSELSEYFRPEDLFVGARVN 510

  Fly   516 LKDFIFHIVSADEYTLMYMEHHPEIFPHANVGVIMEKVKSALQNRMAEFVGSCVPDCTDLEKKRD 580
            ...|:|.:|.||||...|||.:...||.:::.||..|::     |:.|            .|.|:
 Frog   511 FNGFLFILVDADEYVFNYMERNANEFPMSDISVITSKLR-----RIGE------------TKSRE 558

  Fly   581 VFVSFES-------------FKGALISIMGNQISDHEIISLCRHFSAEKSQPNACDRSTVRAAAH 632
            :...||:             |:..|:.|..||:::|||::..|::|. :.:|. .|..::.|.|.
 Frog   559 IKQHFEANDPTGTSHMPYEIFRNLLVDIYANQLTEHEIMTTGRYYSI-RDKPE-IDLGSLTAIAQ 621

  Fly   633 LELKRTLWNARDDLMEHFHHINPTNQPFLPEVKVRSALRGCRLPFSLELIDNILSILNRNECDDI 697
            .:||:..:.....|.:.|.:.:.....:|...|..:..:..::|    |.|:.|.:|.....::
 Frog   622 EQLKKKSFENFSKLSDVFVYNDQEKNGWLSFQKTLTICKAFKIP----LADDFLRVLLEKHTEN- 681

  Fly   698 EVCDLMNFIDVSCG 711
              .|.:|:|.:..|
 Frog   682 --GDQVNYISLVTG 693

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Efhc1.1	NP_573075.1	DM10	82..189	CDD:128921	43/106 (41%)
		DM10	232..370	CDD:128921	65/138 (47%)
		DM10_dom	424..530	CDD:461948	45/110 (41%)
efhc2	NP_001136133.1	DM10	75..180	CDD:128921	42/104 (40%)
		DM10_dom	218..356	CDD:461948	63/137 (46%)
		DM10_dom	414..525	CDD:461948	45/110 (41%)