Protein Alignment CG8952 and TPSAB1

DIOPT Version :10

• Sequence 1: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 85/278 - (30%)
• Similarity: 132/278 - (47%)
• Gaps: 30/278 - (10%)

  Fly     9 LMLVLLAAISVVGQPFDPANSSPIKIDNR--IVSGSDAKLGQFPWQVILKRDA--WDDLLCGGSI 69
            |.|:|||...:..:.:  |..:|.:...|  ||.|.:|...::||||.|:...  |.. .||||:
Human     2 LNLLLLALPVLASRAY--AAPAPGQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMH-FCGGSL 63

  Fly    70 ISDTWVLTAAHC----TNGLSSIFLMFGTVDLFNANALNMTSNNIIIHPD-YNDKLNNDVSLIQL 129
            |...||||||||    ...|:::.:......|:..:.| :..:.||:||. |..::..|::|::|
Human    64 IHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQL-LPVSRIIVHPQFYTAQIGADIALLEL 127

  Fly   130 PEPLTFSANIQAIQLVGQYGDSIDYVGSVATIAGFGYTE-DEYLDYSETLLYAQVEIIDNADCVA 193
            .||:..|:::..:.|  .........|....:.|:|..: ||.|.....|...:|.|::|..|.|
Human   128 EEPVNVSSHVHTVTL--PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDA 190

  Fly   194 IY--GKY------VVVDSTMCAKGFDGSDMSTCTGDSGGPLILYNKTIQQWQQIGINSFVAEDQC 250
            .|  |.|      :|.|..:||   ..:...:|.|||||||:.  |....|.|.|:.|: .|...
Human   191 KYHLGAYTGDDVRIVRDDMLCA---GNTRRDSCQGDSGGPLVC--KVNGTWLQAGVVSW-GEGCA 249

  Fly   251 TYRLPSGYARVSSFLGFI 268
            ....|..|.||:.:|.:|
Human   250 QPNRPGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	77/248 (31%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	77/247 (31%)