Protein Alignment CG8952 and PRSS2

DIOPT Version :10

• Sequence 1: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 82/280 - (29%)
• Similarity: 130/280 - (46%)
• Gaps: 43/280 - (15%)

  Fly     8 SLMLVLLAAISVVGQPFDPANSSPIKIDNRIVSGSDAKLGQFPWQVILKRDAWDDLLCGGSIISD 72
            :|:|:|....:.|..|||.        |::||.|...:....|:||.|.....   .||||:||:
Human     2 NLLLILTFVAAAVAAPFDD--------DDKIVGGYICEENSVPYQVSLNSGYH---FCGGSLISE 55

  Fly    73 TWVLTAAHC-----TNGLSS-------IFLMFG--TVDLFNANALNMTSNNIIIHPDYNDK-LNN 122
            .||::|.||     .:.||.       |.:..|  .:::...|...:.:..||.||.||.: |:|
Human    56 QWVVSAGHCYKSAINSKLSGRGCEYHRIQVRLGEHNIEVLEGNEQFINAAKIIRHPKYNSRTLDN 120

  Fly   123 DVSLIQLPEPLTFSANIQAIQLVGQYGDSIDYVGSVATIAGFGYTEDEYLDYSETLLYAQVEIID 187
            |:.||:|..|...::.:.||.|    ..:....|:.:.|:|:|.|.....||.:.|......::.
Human   121 DILLIKLSSPAVINSRVSAISL----PTAPPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLS 181

  Fly   188 NADCVAIY-GKYVVVDSTMCAKGFDGSDMSTCTGDSGGPLILYNKTIQQWQQIGINSFVAEDQCT 251
            .|:|.|.| ||   :.:.|...||......:|.|||||| ::.|..:|     ||.|:  ...|.
Human   182 QAECEASYPGK---ITNNMFCVGFLEGGKDSCQGDSGGP-VVSNGELQ-----GIVSW--GYGCA 235

  Fly   252 YR-LPSGYARVSSFLGFIAD 270
            .: .|..|.:|.:::.:|.|
Human   236 QKNRPGVYTKVYNYVDWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	72/247 (29%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	74/250 (30%)