Protein Alignment CG8952 and Cfd

DIOPT Version :10

• Sequence 1: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_001071110.1
• Gene: Cfd / 54249
• RGDID: 2498
• Length: 263
• Species: Rattus norvegicus
• Alignment Length: 279
• Identity: 67/279 - (24%)
• Similarity: 124/279 - (44%)
• Gaps: 60/279 - (21%)

  Fly    11 LVLLAAISVVGQPFDPANSSPIKIDNRIVSGSDAKLGQFPWQVILKRDAWDDLLCGGSIISDTWV 75
            ||:|.|...|.||           ..||:.|.:|.....|:...::.:...  :|||:::.:.||
  Rat    10 LVVLEAAVCVAQP-----------RGRILGGQEAMAHARPYMASVQVNGTH--VCGGTLVDEQWV 61

  Fly    76 LTAAHCTNGLSSIFLMFGTVD-----LFNANALNMTS--------NNIIIHPDYN-DKLNNDVSL 126
            |:||||.:|:        |.|     |..|::|:...        .::::||... |.:.:|:.|
  Rat    62 LSAAHCMDGV--------TKDEVVQVLLGAHSLSSPEPYKHLYDVQSVVLHPGSRPDSVEDDLML 118

  Fly   127 IQLPEPLTFSANIQAIQLVGQYGDSIDYVGSVATIAGFGYTEDEYLDYS----ETLLYAQVEIID 187
            .:|....:...:::.:.|  |..|.....|::..:||:|     .:.::    :.|....|.|:|
  Rat   119 FKLSHNASLGPHVRPLPL--QREDREVKPGTLCDVAGWG-----VVTHAGRRPDVLQQLTVSIMD 176

  Fly   188 NADC-VAIYGKYVVVDSTMCAKGFDGSDMSTCTGDSGGPLILYN--KTIQQWQQIGINSFVAEDQ 249
            ...| :..|....:..:.|||   :.:...||.|||||||:..:  :.:..|     .|.|..::
  Rat   177 RNTCNLRTYHDGAITKNMMCA---ESNRRDTCRGDSGGPLVCGDAVEAVVTW-----GSRVCGNR 233

  Fly   250 CTYRLPSGYARVSSFLGFI 268
               |.|..:.||::::.:|
  Rat   234 ---RKPGVFTRVATYVPWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	59/251 (24%)
Cfd	NP_001071110.1	Tryp_SPc	26..252	CDD:238113	59/252 (23%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		1/8 (13%)