Protein Alignment CG8952 and KLK12

DIOPT Version :10

• Sequence 1: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_062544.1
• Gene: KLK12 / 43849
• HGNCID: 6360
• Length: 254
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 69/275 - (25%)
• Similarity: 116/275 - (42%)
• Gaps: 50/275 - (18%)

  Fly     9 LMLVLLAAISVVGQPFDPANSSPIKIDNRIVSGSDAKLGQFPWQVILKRDAWDDLLCGGSIISDT 73
            |.:.||..:..:.|...|          :|.:|::......||||.|....  .|.|||.:|...
Human     3 LSIFLLLCVLGLSQAATP----------KIFNGTECGRNSQPWQVGLFEGT--SLRCGGVLIDHR 55

  Fly    74 WVLTAAHCTNGLSSIFLMFGTVDLFNANALNMT-----SNNIIIHPDY---NDKLNNDVSLIQLP 130
            ||||||||:.  |..::..|...|   :.|:.|     |...:.||.|   :....:|:.|::|.
Human    56 WVLTAAHCSG--SRYWVRLGEHSL---SQLDWTEQIRHSGFSVTHPGYLGASTSHEHDLRLLRLR 115

  Fly   131 EPLTFSANIQAIQLVGQYGDSIDYVGSVATIAGFGYTEDEYLDYSETLLYAQVEIIDNADCVAIY 195
            .|:..::::|.:.|......:    |:...::|:|.|......:.:.|....:.|:.:|.|..:|
Human   116 LPVRVTSSVQPLPLPNDCATA----GTECHVSGWGITNHPRNPFPDLLQCLNLSIVSHATCHGVY 176

  Fly   196 -GKYVVVDSTMCAKGFDGSDMSTCTGDSGGPLILYN--KTIQQWQQIGINSFVAEDQCTYRLPSG 257
             |:  :..:.:||.|..|.|  .|.|||||||:...  :.:..|..:|              |.|
Human   177 PGR--ITSNMVCAGGVPGQD--ACQGDSGGPLVCGGVLQGLVSWGSVG--------------PCG 223

  Fly   258 YARVSSFLGFIADKT 272
            ...:.....:|.:.|
Human   224 QDGIPGVYTYICNST 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	62/241 (26%)
KLK12	NP_062544.1	Tryp_SPc	22..236	CDD:238113	63/242 (26%)