Protein Alignment CG8952 and KLK14

DIOPT Version :10

• Sequence 1: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_071329.3
• Gene: KLK14 / 43847
• HGNCID: 6362
• Length: 251
• Species: Homo sapiens
• Alignment Length: 262
• Identity: 63/262 - (24%)
• Similarity: 110/262 - (41%)
• Gaps: 17/262 - (6%)

  Fly    10 MLVLLAAISVVGQPFDPANSSPIKIDNRIVSGSDAKLGQFPWQVILKRDAWDDLLCGGSIISDTW 74
            |.:||.|:.|:......:...    :|:|:.|........|||..|........||||:::|..|
Human     1 MFLLLTALQVLAIAMTQSQED----ENKIIGGHTCTRSSQPWQAALLAGPRRRFLCGGALLSGQW 61

  Fly    75 VLTAAHCTNGLSSIFLMFGTVDLFNANALNMTSNNIIIHPDYNDKL-NNDVSLIQLPEPLTFSAN 138
            |:|||||...:..:.|....:..:.|....:.....:.||:||.:. :||:.|:||.:|......
Human    62 VITAAHCGRPILQVALGKHNLRRWEATQQVLRVVRQVTHPNYNSRTHDNDLMLLQLQQPARIGRA 126

  Fly   139 IQAIQLVGQYGDSIDYVGSVATIAGFGYTEDEYLDYSETLLYAQVEIIDNADCVAIYGKYVVVDS 203
            ::.|::.    .:....|:...::|:|........|..:|....:.|..:..|...|.: .:...
Human   127 VRPIEVT----QACASPGTSCRVSGWGTISSPIARYPASLQCVNINISPDEVCQKAYPR-TITPG 186

  Fly   204 TMCAKGFDGSDMSTCTGDSGGPLILYNKTIQQWQQIGINSFVAEDQCTYRLPSGYARVSSFLGFI 268
            .:|| |.......:|.|||||||:.      :.|..|:.|:..|.......|..|..:..:..:|
Human   187 MVCA-GVPQGGKDSCQGDSGGPLVC------RGQLQGLVSWGMERCALPGYPGVYTNLCKYRSWI 244

  Fly   269 AD 270
            .:
Human   245 EE 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	56/231 (24%)
KLK14	NP_071329.3	Tryp_SPc	25..247	CDD:238113	57/234 (24%)