DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8952 and modSP

DIOPT Version :9

Sequence 1:	NP_573072.1	Gene:	CG8952 / 32525	FlyBaseID:	FBgn0030688	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_536776.2	Gene:	modSP / 42032	FlyBaseID:	FBgn0051217	Length:	628	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	63/277 - (22%)
Similarity:	86/277 - (31%)	Gaps:	86/277 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SSPIK--------IDNRIVSGSDAKLGQFPWQVILKRDAWDD-----LLCGGSIISDTWVLTAAH 80
            ::|||        |:|.:|          ||.|.|.  .|.:     ..||||:::...|:||||
  Fly   362 ATPIKQFSSGGYTINNTVV----------PWHVGLY--VWHNEKDYHFQCGGSLLTPDLVITAAH 414

  Fly    81 CT--NGLSSIFLMFGTVDLFNANALNMTSNN--------------IIIHPDYNDKLNN---DVSL 126
            |.  .|....:    :.|.|...|.....|.              |.|.|.|..:..|   |::|
  Fly   415 CVYDEGTRLPY----SYDTFRVIAAKFYRNYGETTPEEKRRDVRLIEIAPGYKGRTENYYQDLAL 475

  Fly   127 IQLPEPLTFSANIQAIQLVGQYGDSIDYVGSVATIAGFGYTEDEYLDYSETLLYAQVEIIDNADC 191
            :.|.||...|..|:.|               ..|.|.|...|....|.........:|.......
  Fly   476 LTLDEPFELSHVIRPI---------------CVTFASFAEKESVTDDVQGKFAGWNIENKHELQF 525

  Fly   192 VAIYGKYVVVDSTMCAKG-----------FDGSDMSTCTGDSGGPLI--LYNKTIQQWQQ----- 238
            |....|    .:::|.:.           |.......|.|||||...  |.......|..
  Fly   526 VPAVSK----SNSVCRRNLRDIQADKFCIFTQGKSLACQGDSGGGFTSELPTNAFSTWNTARHFL 586

  Fly   239 IGINSFVAE-DQCTYRL 254
            .|:.|.... |||.:.|
  Fly   587 FGVISNAPNADQCAHSL 603

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	58/261 (22%)
CG8952	NP_573072.1	Tryp_SPc	38..271	CDD:238113	58/260 (22%)
modSP	NP_536776.2	LDLa	27..58	CDD:197566
		LDLa	70..101	CDD:197566
		LDLa	123..157	CDD:197566
		LDLa	167..199	CDD:238060
		CCP	<251..284	CDD:153056
		Sushi	309..354	CDD:278512
		Tryp_SPc	371..616	CDD:214473	60/268 (22%)
		Tryp_SPc	371..591	CDD:304450	55/254 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436908
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030