DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8952 and CG3505

DIOPT Version :9

Sequence 1:	NP_573072.1	Gene:	CG8952 / 32525	FlyBaseID:	FBgn0030688	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_650380.2	Gene:	CG3505 / 41777	FlyBaseID:	FBgn0038250	Length:	360	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	70/294 - (23%)
Similarity:	121/294 - (41%)	Gaps:	61/294 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 AAISVVGQPFDPANSSPIKIDNRIVSGSDAKLGQFPWQVILK--RDAWDDL-LCGGSIISDTWVL 76
            |.:..:..|..|::...::....  :.:|.::.:|||..:::  |...:.: .|||.:|||.:||
  Fly    86 AGLGALTHPLLPSDCGKVRWQRS--NDTDTRIREFPWLALIEYTRGNQEKIHACGGVLISDRYVL 148

  Fly    77 TAAHC-----TNGLSSIFLMFGTVDLFNANALNMTSNN-------------------------II 111
            |||||     |:.|....:..|..|         ||.|                         ::
  Fly   149 TAAHCVAQAATSNLQITAVRLGEWD---------TSTNPDCQYHEDSKVADCAPPYQDIAIEELL 204

  Fly   112 IHPDYN--DKLN-NDVSLIQLPEPLTFSANIQAIQLVGQYGDSIDYVGSVATIAGFGYTEDEYLD 173
            .||.||  |:.. ||::|::|..|...:..:|.|.|..:...:.:....|..:||:..:.
  Fly   205 PHPLYNRTDRTQINDIALVRLASPAKLNDFVQPICLPNKQLRADELEDLVTEVAGWQASS----- 264

  Fly   174 YSETLLYAQVEIIDNADCVAIYG--KYVVVDSTMCAKGFDGSDMSTCTGDSGGPLILYNKTIQQW 236
             |:.:....|.|....:|...|.  :..:..|.:|  |...|  ..|.|::||||:|:..  ..:
  Fly   265 -SQRMRKGYVTISSIEECQRKYASQQLRIQASKLC--GLTNS--QECYGNAGGPLMLFKN--DGY 322

  Fly   237 QQIGINSFVAEDQCTYRLPSGYARVSSFLGFIAD 270
            ...|:.||..........|..|.||:|::.:|.|
  Fly   323 LLGGLVSFGPVPCPNPDWPDVYTRVASYIDWIHD 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	65/268 (24%)
CG8952	NP_573072.1	Tryp_SPc	38..271	CDD:238113	67/271 (25%)
CG3505	NP_650380.2	CLIP	30..82	CDD:288855
		Tryp_SPc	111..356	CDD:238113	66/265 (25%)
		Tryp_SPc	111..354	CDD:214473	65/263 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436488
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940