Protein Alignment CG8952 and KLK2

DIOPT Version :10

• Sequence 1: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 79/277 - (28%)
• Similarity: 121/277 - (43%)
• Gaps: 42/277 - (15%)

  Fly    11 LVLLAAISVVGQPFDPANSSPIKIDNRIVSGSDAKLGQFPWQVILKRDAWDDLLCGGSIISDTWV 75
            |||..|:||     ....:.|: |.:|||.|.:.:....||||.:....|..  |||.::...||
Human     4 LVLSIALSV-----GCTGAVPL-IQSRIVGGWECEKHSQPWQVAVYSHGWAH--CGGVLVHPQWV 60

  Fly    76 LTAAHCTNGLSSIFLMFGTVDLFNANALNMTSNNIII-----HPDYNDKL------------NND 123
            ||||||....|.::|  |..:||....   |...:.:     ||.||..|            ::|
Human    61 LTAAHCLKKNSQVWL--GRHNLFEPED---TGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHD 120

  Fly   124 VSLIQLPEPLTFSANIQAIQLVGQYGDSIDYVGSVATIAGFGYTEDEYLDYSETLLYAQVEIIDN 188
            :.|::|.||...:..::.:.|..|.    ..:|:....:|:|..|.|......:|....:.::.|
Human   121 LMLLRLSEPAKITDVVKVLGLPTQE----PALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSN 181

  Fly   189 ADCVAIYGKYVVVDSTMCAKGFDGSDMSTCTGDSGGPLILYNKTIQQWQQIGINSFVAEDQCTYR 253
            ..|...|.: .|.:..:||..:.|. ..||.|||||||:. |..:|     ||.|:..|......
Human   182 DMCARAYSE-KVTEFMLCAGLWTGG-KDTCGGDSGGPLVC-NGVLQ-----GITSWGPEPCALPE 238

  Fly   254 LPSGYARVSSFLGFIAD 270
            .|:.|.:|..:..:|.|
Human   239 KPAVYTKVVHYRKWIKD 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	69/247 (28%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	70/250 (28%)