DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8952 and CG10764

DIOPT Version :9

Sequence 1:	NP_573072.1	Gene:	CG8952 / 32525	FlyBaseID:	FBgn0030688	Length:	276	Species:	Drosophila melanogaster
Sequence 2:	NP_611213.2	Gene:	CG10764 / 36962	FlyBaseID:	FBgn0034221	Length:	523	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	74/277 - (26%)
Similarity:	123/277 - (44%)	Gaps:	36/277 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SLMLVLLAAISVVGQPFDPANSSPIKIDNR--IVSGSDAKLGQFPWQVILKRDAWDDLLCGGSII 70
            |:.|:.|..:.|..........:|..|..|  |..|.||......|...:...:  |..|||:||
  Fly     6 SVALLSLLTLCVTENEHFKFLETPCGISTRPKISGGDDAAEPNSIWMAAIFNSS--DFQCGGTII 68

  Fly    71 SDTWVLTAAHCTNGLSSIFLMFGTVDLFNANALNMTSNNIIIHPDY-NDKLNNDVSLIQLPEPLT 134
            ...:||:||||......:::..|..:: |..|...|..|:.:|.|: ..:..||:.|:||.|.:.
  Fly    69 HMRFVLSAAHCLVRGYDLYVRLGARNI-NEPAAVHTVINVFVHHDFIASEYRNDIGLLQLSESIV 132

  Fly   135 FSANIQAIQLVGQYGDSID--YVGSVATI-----AGFGYTEDEYLDYSETLLYAQVEIIDNADCV 192
            ::..:|.|.:.      :|  ..|||..:     .|:|....:.....:|:....::   ..:|.
  Fly   133 YTVRVQPICIF------LDPALKGSVEKLKTFRALGWGNRNGKLSIMLQTIYLLHLK---RNECK 188

  Fly   193 AIYGKYVVVDSTMCAKGFDGSDMSTCTGDSGGPL---ILY--NKTIQQWQQIGINSFVAEDQCTY 252
            ... .:.:....:||...:|   .||.|||||||   ||:  ||:.:  .|:||.|| .:.:|
  Fly   189 RKL-NFNLNSRQICAGTKNG---DTCRGDSGGPLSTNILFPSNKSYE--VQLGIVSF-GDPEC-- 244

  Fly   253 RLPSGYARVSSFLGFIA 269
            |....|..|:|::.:|:
  Fly   245 RGVGVYTDVTSYVDWIS 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	67/245 (27%)
CG8952	NP_573072.1	Tryp_SPc	38..271	CDD:238113	67/245 (27%)
CG10764	NP_611213.2	Tryp_SPc	37..260	CDD:214473	66/243 (27%)
		Tryp_SPc	38..263	CDD:238113	67/245 (27%)
		Tryp_SPc	317..512	CDD:214473
		Tryp_SPc	317..512	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45436509
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24260
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030