Protein Alignment CG8952 and KLK5

DIOPT Version :10

• Sequence 1: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_036559.1
• Gene: KLK5 / 25818
• HGNCID: 6366
• Length: 293
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 60/238 - (25%)
• Similarity: 109/238 - (45%)
• Gaps: 18/238 - (7%)

  Fly    36 NRIVSGSDAKLGQFPWQ-VILKRDAWDDLLCGGSIISDTWVLTAAHCTNGLSSIFL-MFGTVDLF 98
            :||::|||..:...||| .:|.|.  :.|.||..::...|:||||||...:..:.| .:....::
Human    65 SRIINGSDCDMHTQPWQAALLLRP--NQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVY 127

  Fly    99 NANALNMTSNNIIIHPDYNDK-LNNDVSLIQLPEPLTFSANIQAIQLVGQYGDSIDYVGSVATIA 162
            .:..........|.||.|:.. .:||:.||:|...:..:.:::.|. |..:..|   .|:...::
Human   128 ESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPIN-VSSHCPS---AGTKCLVS 188

  Fly   163 GFGYTEDEYLDYSETLLYAQVEIIDNADCVAIYGKYVVVDSTMCAKGFDGSDMSTCTGDSGGPLI 227
            |:|.|:...:.:.:.|....:.::....|...|.:.  :|.||...| |.:...:|.||||||::
Human   189 GWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQ--IDDTMFCAG-DKAGRDSCQGDSGGPVV 250

  Fly   228 LYNKTIQQWQQIGINSFVAEDQCTYRLPSGYARVSSFLGFIAD 270
            . |.::|     |:.|:..........|..|..:..|..:|.:
Human   251 C-NGSLQ-----GLVSWGDYPCARPNRPGVYTNLCKFTKWIQE 287

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	59/233 (25%)
KLK5	NP_036559.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..68		1/2 (50%)
		Tryp_SPc	66..285	CDD:214473	59/233 (25%)