DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8952 and Tmprss11d

DIOPT Version :10

Sequence 1:NP_573072.1 Gene:CG8952 / 32525 FlyBaseID:FBgn0030688 Length:276 Species:Drosophila melanogaster
Sequence 2:NP_663536.1 Gene:Tmprss11d / 231382 MGIID:2385221 Length:417 Species:Mus musculus


Alignment Length:259 Identity:80/259 - (30%)
Similarity:122/259 - (47%) Gaps:43/259 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    35 DNRIVSGSDAKLGQFPWQVILKRDAWDDLLCGGSIISDTWVLTAAHC------------TNGLSS 87
            :.||:.|..|:.|.:||||.|:.:....  |||::||:.||||||||            |.|:|:
Mouse   183 EERIIGGMQAEPGDWPWQVSLQLNNVHH--CGGALISNMWVLTAAHCFKSYPNPQYWTATFGVST 245

  Fly    88 IFLMFGTVDLFNANALNMTSNNIIIHPDYND-KLNNDVSLIQLPEPLTFSANIQAIQLVGQYGDS 151
            :           :..|.:....|:.|..|:. ..:||::::||...:.||.||..:.|.....:.
Mouse   246 M-----------SPRLRVRVRAILAHDGYSSVTRDNDIAVVQLDRSVAFSRNIHRVCLPAATQNI 299

  Fly   152 IDYVGSVATIAGFGYTEDEYLDYS----ETLLYAQVEIIDNADCVAIYG-KYVVVDSTMCAKGFD 211
            |.  ||||.:.|:|     .|.|.    ..|...:|.||.:.:|....| ...|:...:|| |..
Mouse   300 IP--GSVAYVTGWG-----SLTYGGNAVTNLRQGEVRIISSEECNTPAGYSGSVLPGMLCA-GMR 356

  Fly   212 GSDMSTCTGDSGGPLILYNKTIQQWQQIGINSFVAEDQCTY-RLPSGYARVSSFLGFIADKTGI 274
            ...:..|.|||||||: ...:.:.|..:||.|:  ..||.. ..|..|.||:::..:|..:|||
Mouse   357 SGAVDACQGDSGGPLV-QEDSRRLWFVVGIVSW--GYQCGLPNKPGVYTRVTAYRNWIRQQTGI 417

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8952NP_573072.1 Tryp_SPc 37..268 CDD:214473 76/249 (31%)
Tmprss11dNP_663536.1 SEA 48..140 CDD:460188
Tryp_SPc 186..414 CDD:238113 76/251 (30%)
Blue background indicates that the domain is not in the aligned region.

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