Protein Alignment CG8952 and KLK8

DIOPT Version :10

• Sequence 1: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_653088.1
• Gene: KLK8 / 11202
• HGNCID: 6369
• Length: 305
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 74/254 - (29%)
• Similarity: 116/254 - (45%)
• Gaps: 27/254 - (10%)

  Fly    23 PFDPANSSPIKIDNRIVSGSDAKLGQFPWQVILKRDAWDDLLCGGSIISDTWVLTAAHCTNGLSS 87
            |..||.......:::::.|.:.:....|||..|.:.  ..|||||.::...||||||||.....:
Human    63 PLPPAAGHSRAQEDKVLGGHECQPHSQPWQAALFQG--QQLLCGGVLVGGNWVLTAAHCKKPKYT 125

  Fly    88 IFLMFGTVDLFNANALNMTSNNI--IIHPDYN----DKLNNDVSLIQLPEPLTFSANIQAIQLVG 146
            :.|  |...|.|.:........:  |.||.||    :..|:|:.|:||.:..:..:.::.|.|
Human   126 VRL--GDHSLQNKDGPEQEIPVVQSIPHPCYNSSDVEDHNHDLMLLQLRDQASLGSKVKPISL-- 186

  Fly   147 QYGDSIDYVGSVATIAGFGYTEDEYLDYSETLLYAQVEIIDNADCVAIY-GKYVVVDSTMCAKGF 210
              .|.....|...|::|:|.......::.:||..|:|:|.....|...| |:  :.|..:||...
Human   187 --ADHCTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQ--ITDGMVCAGSS 247

  Fly   211 DGSDMSTCTGDSGGPLILYNKTIQQWQQIGINSFVAEDQC-TYRLPSGYARVSSFLGFI 268
            .|:|  ||.|||||||:. :..:|     ||.|: ..|.| ....|..|..:..:|.:|
Human   248 KGAD--TCQGDSGGPLVC-DGALQ-----GITSW-GSDPCGRSDKPGVYTNICRYLDWI 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	70/238 (29%)
KLK8	NP_653088.1	Tryp_SPc	77..297	CDD:214473	70/238 (29%)