Protein Alignment CG8952 and PRSS21

DIOPT Version :10

• Sequence 1: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_006790.1
• Gene: PRSS21 / 10942
• HGNCID: 9485
• Length: 314
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 85/276 - (30%)
• Similarity: 132/276 - (47%)
• Gaps: 52/276 - (18%)

  Fly     3 LNSERSLMLVLLAAISVVGQPFDPANSSPIK-------IDNRIVSGSDAKLGQFPWQVILKRDAW 60
            :.:..:|:|.||.|.:.:.:| :...::|:.       |.:|||.|.||:||::|||..|:  .|
Human     1 MGARGALLLALLLARAGLRKP-ESQEAAPLSGPCGRRVITSRIVGGEDAELGRWPWQGSLR--LW 62

  Fly    61 DDLLCGGSIISDTWVLTAAHCTNGLSSI------FLMFGTVDLFNANALNMTS------------ 107
            |..:||.|::|..|.||||||....|.:      .:.||.:       .:|.|
Human    63 DSHVCGVSLLSHRWALTAAHCFETYSDLSDPSGWMVQFGQL-------TSMPSFWSLQAYYTRYF 120

  Fly   108 -NNIIIHPDYNDKLNNDVSLIQLPEPLTFSANIQAIQLVG---QYGDSIDYVGSVATIAGFGY-T 167
             :||.:.|.|......|::|::|..|:|::.:||.|.|..   ::.:..|     ..:.|:|| .
Human   121 VSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQASTFEFENRTD-----CWVTGWGYIK 180

  Fly   168 EDEYLDYSETLLYAQVEIIDNADCVAIYGKYV----VVDSTMCAKGFDGSDMSTCTGDSGGPLIL 228
            |||.|....||...||.||:|:.|..::.||.    :....:||....|. ...|.|||||||..
Human   181 EDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKDIFGDMVCAGNAQGG-KDACFGDSGGPLAC 244

  Fly   229 YNKTIQQWQQIGINSF 244
            ....:  |.|||:.|:
Human   245 NKNGL--WYQIGVVSW 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	77/235 (33%)
PRSS21	NP_006790.1	Tryp_SPc	42..283	CDD:238113	76/234 (32%)