Protein Alignment CG8952 and tmprss6

DIOPT Version :10

• Sequence 1: NP_573072.1
• Gene: CG8952 / 32525
• FlyBaseID: FBgn0030688
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: XP_004913946.2
• Gene: tmprss6 / 100489045
• XenbaseID: XB-GENE-1011573
• Length: 806
• Species: Xenopus tropicalis
• Alignment Length: 252
• Identity: 77/252 - (30%)
• Similarity: 125/252 - (49%)
• Gaps: 32/252 - (12%)

  Fly    37 RIVSGSDAKLGQFPWQVILKRDAWDDLLCGGSIISDTWVLTAAHCTNGLS-------SIFLMFGT 94
            |:|.|:.|:.|::|||..|:  ...:.:|||::::|.|:||||||....|       :::|  |.
 Frog   570 RLVGGTQAQEGEWPWQASLQ--VRGEHICGGTLVADQWILTAAHCFTPESYASPEVWTVYL--GK 630

  Fly    95 VDLFNANALNMTSN--NIIIHPDYN-DKLNNDVSLIQLPE--PLTFSANIQAIQLVGQYGDSIDY 154
            |.|..:....:...  .::|||.|: |..:.||:|:.|..  ||| |.::|.|.|    ..|..:
 Frog   631 VRLSRSTQKELAFKVIRLVIHPFYDEDSHDYDVALVLLDHLVPLT-SPHVQPICL----PSSTHH 690

  Fly   155 --VGSVATIAGFGYTEDEYLDYSETLLYAQVEIIDNADCVAIYGKYVVVDSTMCAKGFDGSDMST 217
              .||...:.|:|..: |....|:.|....::::....|..:| :|.:....:||...||| ...
 Frog   691 FPTGSSCWVTGWGSVK-ENGPTSDVLQKVDIQLVAQDICTELY-RYQISPRMLCAGYRDGS-KDA 752

  Fly   218 CTGDSGGPLILYNKTIQ-QWQQIGINSFVAEDQCTY-RLPSGYARVSSFLGFIADKT 272
            |.||||.||:.  ||.. :|.|.|:.|:.|  .|.. |....|:|::..:.:|...|
 Frog   753 CQGDSGSPLVC--KTASGRWFQAGLVSWGA--GCGIPRYFGVYSRITRLVQWIESIT 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8952	NP_573072.1	Tryp_SPc	37..268	CDD:214473	75/246 (30%)
tmprss6	XP_004913946.2	SEA	77..174	CDD:460188
		CUB	235..303	CDD:412131
		LDLa	448..478	CDD:238060
		LDLa	480..514	CDD:238060
		LDLa	525..560	CDD:238060
		Tryp_SPc	572..804	CDD:238113	75/247 (30%)