DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpIIIC160 and ubxn7

DIOPT Version :9

Sequence 1:	NP_001096987.2	Gene:	RpIIIC160 / 32524	FlyBaseID:	FBgn0030687	Length:	1383	Species:	Drosophila melanogaster
Sequence 2:	NP_001001951.1	Gene:	ubxn7 / 402913	ZFINID:	ZDB-GENE-040704-8	Length:	505	Species:	Danio rerio

Alignment Length:	461	Identity:	88/461 - (19%)
Similarity:	151/461 - (32%)	Gaps:	140/461 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   410 GPSMHPGANYVQQRGSSFKKYLAYGNREKVAQEL--KCGD----VVERHLRDGDIVLFNRQPSLH 468
            |.:..||.|.:.|:.::..     |..|.|.:.:  .|.:    .|...|..|.|.   .:||..
Zfish     5 GDASAPGVNGLIQQFTAIT-----GATESVGKHMLEACNNNLEMAVTMFLDGGGIA---EEPSTS 61

  Fly   469 KMSIMCHRAKVQPQRTFRFNECACTPYNADFDGDEMNLHLPQTEEARAEALILMGNQSNLVTPKN 533
            ..|.....:::.|..                  ||:...:||.:|...|...|.|      .||.
Zfish    62 ASSARASSSRIPPVE------------------DEVRAPIPQKQEILVEPEPLFG------VPKR 102

  Fly   534 ---GEILIAATQDFITGGYLLTQKEVFLTKEEAMQLAACFLANEDSTMHIKLPPPALLKPRRLWT 595
               ...:....:||        |.|....::|....:|                          .
Zfish   103 RRPARSIFDGFRDF--------QTETIRQEQELRNGSA--------------------------V 133

  Fly   596 GKQMFSL--LMRPNDDSQVRLNMVNKGRNYTRNKDLCSNDSW--IHIRNSELMCGVMDKATMGSG 656
            .|::.:|  |.||      .:.:::||...|........:.|  |:|:|      |.|.|.
Zfish   134 DKKLSTLADLFRP------PIELMHKGSFETAKDSGQLENKWLMINIQN------VQDFAC---- 182

  Fly   657 TKQCIFYLLLRDFGESHATKAM-------WRL-------ARIASYFLQNRGFSFGISDVTPSKKL 707
              ||    |.||...:.|.|.:       |::       .|...::..|:.....|.|....:|:
Zfish   183 --QC----LNRDVWSNDAVKTIIREHFIFWQVYHDSEEGQRYIQFYKLNKFPYISILDPRTGQKM 241

  Fly   708 LQHKELLLNNGYAKCNEYIELLKAGTLQCQPGCTPEETLESVMLRELS-------AIREQAAKTC 765
            ::..:|.:::...:...:  |.:.|.|..|....|.:...|..|.:.|       |||....:|.
Zfish   242 VEWNQLDVSSFMDQVTGF--LSEHGQLDGQSSQPPAKRARSESLIDASEDSQLEAAIRASLQETH 304

  Fly   766 F------AELHPTNSALIMALSGSKG-SNINISQMIACVGQQAISG---------KRVPNGFENR 814
            :      ||....:.:.....|.|:| .:::.|...|..|:.::.|         .|..:...:|
Zfish   305 YESTQEKAESRSDDDSDAEPFSDSEGLISVDGSDNEAGAGEDSLDGHTSTELAPPTRSDSPAHHR 369

  Fly   815 ALPHFE 820
            ..||.|
Zfish   370 KSPHKE 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpIIIC160	NP_001096987.2	PRK08566	13..919	CDD:236292	88/461 (19%)
		RNAP_III_RPC1_N	24..889	CDD:259847	88/461 (19%)
		RNA_pol_Rpb1_5	839..1304	CDD:282807
		RNAP_III_Rpc1_C	1013..1353	CDD:132723
ubxn7	NP_001001951.1	UBA_UBXD7	15..50	CDD:270530	6/39 (15%)
		UAS	151..263	CDD:239256	25/129 (19%)
		UBQ	424..505	CDD:294102
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0086
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900