Protein Alignment RpIIIC160 and rpoa-1

DIOPT Version :9

• Sequence 1: NP_001096987.2
• Gene: RpIIIC160 / 32524
• FlyBaseID: FBgn0030687
• Length: 1383
• Species: Drosophila melanogaster
• Sequence 2: NP_001022450.1
• Gene: rpoa-1 / 175015
• WormBaseID: WBGene00012999
• Length: 1737
• Species: Caenorhabditis elegans
• Alignment Length: 1796
• Identity: 461/1796 - (25%)
• Similarity: 706/1796 - (39%)
• Gaps: 519/1796 - (28%)

  Fly     2 PKEQFRASALNKKISHVQFGISGADEIQQEALVRIISKNLYQAQRQPVPYGVLDRRMGISTKDAM 66
            |..||....|.....|         ||.:.::::|.....:.....|:..|:.|..:|......|
 Worm    11 PYMQFSNFKLRSYFPH---------EIDKLSVLKITQTKTFDEVGHPIAGGLYDPILGPDNTFDM 66

  Fly    67 CETCGQGLNECIGHFGYLDLALPVFHIGHFRSTINILQMICKVCAHVMLKPED------------ 119
            |.||.|....|.||.|::.||:|||:...|:.|.|:|:..|..|..:..|.:.
 Worm    67 CMTCNQYERHCPGHMGHIQLAVPVFNPLLFQFTYNLLKGSCVHCHRLTCKGDGVNARMLLAQLRC 131

  Fly   120 ------------RQLYEKKLHNPN----------------FSYLGKKALHVQMLAKA-------- 148
                        ..:...|:.|.:                .:.|..|.|......|:
 Worm   132 FELGVEHVAFDLESILRDKIANADLFGDDDSKTFNDVDACIAQLANKPLSELTAFKSMPTKNSVQ 196

  Fly   149 ---------------KKVTKCPHCGSPNGGVKKGPGLLKILHDPYK-----GRKMDSLFTSNMNE 193
                           |::.|||.|.:.| ||.:..|...||.|...     |:...::.....|.
 Worm   197 LKKDIITEFLRSHLFKRLQKCPLCKNRN-GVLRNDGARSILIDFTSGARGGGKSKKAIIIIGDNG 260

  Fly   194 MLRSTQTNRD----------------------LNSTLGNYSTAE--------------------- 215
            ....:.|:.|                      |...:.|..|.|
 Worm   261 YNEESSTDEDEEKKGGGGAEVTGDVVDLDEGSLEMQMKNVRTGECDKLAWRGAEVREHFRMLFKN 325

  Fly   216 ------ELTPLMVLDLFEQIPQRDVALLGMCSHDAHPKHLIVTRVFVPPACIRPSVLSEVKAGTT 274
                  :|.|::|    :::...|:    :|..|.    |.:.|:.|||...||  :...|....
 Worm   326 DGKLLLKLFPMLV----DELNGEDM----ICPLDG----LFLERILVPPKKFRP--IRMFKGAQY 376

  Fly   275 EDDLTMKQSEILLINDVIQRHMA-----TGGKI-ELI-------------HEDWDFLQLHVALYF 320
            ||..|:...::|...:.|.....     |..:: |||             |:.:..|||.....|
 Worm   377 EDPQTLNLRKVLEATETISAISLIMKGDTSAQLKELIANRVRGKTINAQMHDAYLQLQLRANAIF 441

  Fly   321 HSEISGIPINMAPKKTTRGIVQRLKGKQGRFRCNLSGKRVDFSGRTVISPDPNLMINQVGVPVRV 385
            ..:     :|...:.:..||.|.|:.|||.||.::.||||:|:.|:||:|||.|.|:::|:|...
 Worm   442 DQD-----LNKGDRDSIAGIKQILEKKQGLFRMHMMGKRVNFACRSVITPDPYLDIDEIGIPDIF 501

  Fly   386 AKILTYPERVNPANIRHMRELVRNGPSMHPGANYV----------------QQRGSSFKKYLAYG 434
            ||.||:.|.||..|:..|:.|:|.||..|||||:.                ::|.....|.|...
 Worm   502 AKKLTFTEPVNAFNVNEMKGLLRQGPHQHPGANFFVEPSGKKTMLGDKPEEKKRRMQMAKTLNAA 566

  Fly   435 NREKVAQELKCGDVVERHLRDGDIVLFNRQPSLHKMSIMCHRAKV-QPQRTFRFNECACTPYNAD 498
            ..|.:.|..|    |.||:::||:::.||||||||.||:.|||:| ..||..|.|...|..||||
 Worm   567 TTENLRQTPK----VLRHMKNGDMIMMNRQPSLHKPSILGHRARVLTGQRALRMNYAPCKAYNAD 627

  Fly   499 FDGDEMNLHLPQTEEARAEALILMGNQSNLVTPKNGEILIAATQDFITGGYLLTQKEVFLTKEEA 563
            |||||||.||.|:..|:.|...:....||.:.||:...|:...||.:..|.||:.::.||.||:.
 Worm   628 FDGDEMNGHLVQSHIAQTEVREIANVGSNFLVPKDATPLLGLIQDHVVSGVLLSVRDRFLNKEDF 692

  Fly   564 MQLAACFLANEDSTMHIKLPPPALLKPRRLWTGKQMFSLLMR---PNDDSQVRLNMVNKGRNYTR 625
            |.|.....|  ..:..|::|||.:|.|:|||||||:.:.:::   |  |.:..:|:..|.:....
 Worm   693 MHLVLASFA--QYSKRIEIPPPTILYPKRLWTGKQVITTIVKNCIP--DGKPLINLDGKAKTPLS 753

  Fly   626 NKDLC------------SNDSWIHIRNSELMCGVMDKATMGS---GTKQCIFYLLLRDFGESHAT 675
                |            .::|.:..|..||:.||:|||..|:   |...|.|.|    :|.....
 Worm   754 ----CWIVPGFDAPQFDMSESHVVFRQGELLVGVLDKAHFGATQFGLAHCAFEL----YGHRCGV 810

  Fly   676 KAMWRLARIASYFLQNRGFSFGISDVTPSKKLLQHKELLLNNGYAKCNEYI--------ELLKAG 732
            :.:...:|:.:.:||..||:.|::|:           |::.:...|..|.:        :::|..
 Worm   811 QLLSCFSRLFTTYLQFHGFTLGVADI-----------LVVKDADGKRKEAVMESRTIGNQVVKTA 864

  Fly   733 --------------TL---QCQP---GCTPEETLESVMLRELSAIREQAAKTC----FAELHPTN 773
                          ||   .|.|   | |..:.|:..|.:.::...:...|:|    ...|.|.|
 Worm   865 FGLPDTATPAEIKRTLAATYCNPRGQG-TDVKMLDFGMKQGIAKYNDAITKSCVPTGLLRLFPQN 928

  Fly   774 SALIMALSGSKGSNINISQMIACVGQQAISGKRVPNGFENRALPHFERHSAIPAARGFVQNSFYS 838
            :..:|..||:|||.:|..|:..|:||..:.|||:......|.||.|......|.|.|::...|.:
 Worm   929 ALQLMIQSGAKGSAVNAIQISGCLGQIELEGKRMAVTIAGRTLPSFRCFDPSPRAGGYIDQRFLT 993

  Fly   839 GLTPTEFFFHTMAGREGLVDTAVKTAETGYLQRRLVKCLEDLVVHYDGTVRNAVNEMVDTIYGGD 903
            |:.|.|.|||||||||||:||||||:.:|||||.::|.||.:.||||.|||:....::...||.|
 Worm   994 GMNPQELFFHTMAGREGLIDTAVKTSRSGYLQRCIIKHLEGIRVHYDSTVRDHDGSVIQFRYGED 1058

  Fly   904 GLDPVSMETRNKPVDLVHQYDNLR----AQHPQG-KDRPLNAEEMSEALETLLRTPEFAE----- 958
            |:|.......||.. :....|||.    |..|:| .|.....:|..:..:.:::..:.||
 Worm  1059 GMDTTKATFLNKKT-MPFLEDNLEAVTLASKPEGVTDADFGIKETEKRYKKIVKWKKKAEKSGKS 1122

  Fly   959 --------ARDDFKLDVRNHINTVSKRIGQL--------QKRY-----EKC---ID--------- 990
                    |..:|..:   ||....|||..:        :::|     :||   :|
 Worm  1123 GTKKSYFSAFTNFSAE---HIGMEKKRILAMWFELSLEEREQYARGIPKKCPEAVDERFNPTCKL 1184

  Fly   991 ------LCHQIECLTTEQLLQFVRRIND--------------RYNRAVTEPGTAVGAIAAQSIGE 1035
                  :..:||...|.:    |::::|              :..|::.:||..||.:|||||||
 Worm  1185 GALPEKMLDEIEGFCTRR----VKKVDDEEPPKEVLKRTLYWKGMRSLADPGENVGLLAAQSIGE 1245

  Fly  1036 PGTQMTLKTFHFAGVASMNITQGVPRIVEII-NATKTISTP----------------IITAELEN 1083
            |.|||||.||||||...||:|.|:||:.||: .|:|:|:||                .|..||:.
 Worm  1246 PSTQMTLNTFHFAGRGEMNVTLGIPRLREILMTASKSIATPSASIAVIAGTSRDRIDSIKRELDR 1310

  Fly  1084 CHSMEFARQVKARIEKTTLAELSSYVEVVCGPYSCYLAIGVDMARIKLLGL-HIDLDTIVFS--- 1144
            .:..:..:..... ||.||.:..|     |..|  :|.|.:..|..:.||. |:....|:..
 Worm  1311 VYLKQLLKNFSLE-EKITLTQNQS-----CRRY--HLRIDILAAEKRELGARHLKRSQIMEEIEK 1367

  Fly  1145 --ILKSRMRVKPTQVEVV----------------------------------------------- 1160
              ||:....:|....|:.
 Worm  1368 RFILRVAQAIKKKYHEITDYQQMSHRTMRQGNMAAGIETGGTKNRGLQGPDNGDSSDEEADGGRE 1432

  Fly  1161 ---------------------ASQSRIVVRVE---------------------ATRTSTINA--- 1180
                                 ..:.|:.||.|                     .|....:|:
 Worm  1433 ADAAEARLHRRHRDEGADYEGEDEERVEVREEEEPMDSDSEDVKKEGLDGEDQTTEPLLVNSSRI 1497

  Fly  1181 -ELARLALSLQNV-----------VVAGLPNINRAVIAVDD----------ARQPPTYKLCIE-- 1221
             .:.||:.::.:.           ||..||..|:..:.|..          ..|.|..:.|:|
 Worm  1498 QSVQRLSENISSYTYDVKSNKWCEVVFELPLRNKTKMDVSSIVEKEVELFIVHQTPGIERCVETT 1562

  Fly  1222 --------------GYGLR---------DVIATYGVVGKRTRSNNICEIYQTLGIEAARTIIMSE 1263
                          |..|.         ||.:.|        ||::..|.:..|:||....|.:|
 Worm  1563 EQKNGKEMTILQTQGVNLAAFFKHADVLDVNSVY--------SNDLNLILENYGVEACSKAITTE 1619

  Fly  1264 ITEVMEGHGMSVDWRHIMLLASQMTARGEVLGITRHGLAKMRESVFNLASFEKTADHLFDAAYYG 1328
            :..|...:|:.|..||:.|.|..||..|::....| |......|.....:||.|...|.:|..:|
 Worm  1620 MNNVFAVYGIEVSKRHLSLTADYMTFTGQIQPFNR-GAMSSSSSPLQKMTFETTMAFLREALLHG 1683

  Fly  1329 QTDAINGVSERIILGMPACIGTGIFKLL---------QQHE 1360
            :.|.:|..|.|:::|.....|||.|.||         ::||
 Worm  1684 EEDNVNSPSARLVMGALPRGGTGSFDLLLDTKMQSEREEHE 1724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpIIIC160	NP_001096987.2	PRK08566	13..919	CDD:236292	310/1108 (28%)
		RNAP_III_RPC1_N	24..889	CDD:259847	300/1067 (28%)
		RNA_pol_Rpb1_5	839..1304	CDD:282807	169/689 (25%)
		RNAP_III_Rpc1_C	1013..1353	CDD:132723	116/501 (23%)
rpoa-1	NP_001022450.1	PRK14977	10..1713	CDD:184940	459/1783 (26%)
		RNAP_I_RPA1_N	23..1040	CDD:259844	298/1073 (28%)
		RNAP_I_Rpa1_C	1223..1711	CDD:132722	117/504 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D591636at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920