DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL3 and Mrpl3

DIOPT Version :9

Sequence 1:	NP_511166.2	Gene:	mRpL3 / 32523	FlyBaseID:	FBgn0030686	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_444389.2	Gene:	Mrpl3 / 94062	MGIID:	2137204	Length:	348	Species:	Mus musculus

Alignment Length:	364	Identity:	142/364 - (39%)
Similarity:	197/364 - (54%)	Gaps:	34/364 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GLRLSGNSSVLVTQVRDKGHLSRP---RLRNPQWFLR----KEITKYNDLMTAENKQFVNE-VGT 67
            |.||...:...|.....:|..:.|   |.:|..:|:|    |..|.:::.::.||..||.: |..
Mouse     3 GWRLLAQAGARVLGCGARGLGADPGLERRKNILFFVRNLHSKSSTWWDEHLSEENLSFVKQLVSD 67

  Fly    68 NNFGVPAVIKDSLVKTAGPTANEA----VWTPNLRRCGVIARKIGQYPLWLKNGERIRTTLLQIV 128
            .|       |..|.....|..:|.    .|.|...|.|:||.|:|..|||.|:|::...||||:.
Mouse    68 EN-------KTQLTSKLNPLKDEPWPLHPWEPGSFRVGLIALKLGMMPLWTKDGQKHAVTLLQVQ 125

  Fly   129 DNHVIKYIPPEEYLPAQVPTVANLHKRGCILVGSETTNPALLTKEYAGIFRNSGVLPKKNLARFI 193
            |.||:||.|.|::          ..|...:.||.:|.:...........:|:.|:.||:....|.
Mouse   126 DCHVLKYTPKEDH----------NGKIAALTVGGKTVSRFYKPDSRLEFYRDLGLPPKQIHKIFH 180

  Fly   194 VSPEAQLAPGTPLNVNHFRVGDFVDVRGKTVDHGFQGVVKRHGFKGMPASHGVTKTHRRAGNIGG 258
            |:..|.:.|||||...|||.|.:|||..||:..|||||:||.||||.|||||.||||||.|.| .
Mouse   181 VTDNAVIKPGTPLYAAHFRPGQYVDVTAKTIGKGFQGVMKRWGFKGQPASHGQTKTHRRPGAI-S 244

  Fly   259 GGEKGRVWPGTKMPGHMGNRWRIIKGLRVWRINTKYNVMWVQGSSVAGPTGGLVYIYDTILPTRK 323
            .|:..||||||||||.|||:.|.:.||:|||:|||:|:::|.| ||.|....||.|.|:.||..|
Mouse   245 TGDIARVWPGTKMPGRMGNQNRTVYGLKVWRVNTKHNIIYVNG-SVPGHKNCLVKIKDSTLPAYK 308

  Fly   324 NK-EAPPFPTFY--GEPQQDGDDVWYEQVHNFKSESITY 359
            :. :..||||::  |:.::..:|::.|.|......|||:
Mouse   309 DSCKNLPFPTYFPDGDEEELPEDLFDESVWQPSEPSITF 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL3	NP_511166.2	RplC	101..314	CDD:294230	101/212 (48%)
Mrpl3	NP_444389.2	Ribosomal_L3	2..340	CDD:278714	139/355 (39%)
Mrpl3	NP_444389.2	L3_bact	98..300	CDD:274684	101/213 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837871
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0087
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31431
Inparanoid	1	1.050	219	1.000	Inparanoid score	I3563
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55656
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003599
OrthoInspector	1	1.000	-	-		oto93829
orthoMCL	1	0.900	-	-		OOG6_100949
Panther	1	1.100	-	-	LDO	PTHR11229
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1153
SonicParanoid	1	1.000	-	-		X2474
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790