DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mRpL3 and Mrpl3

DIOPT Version :9

Sequence 1:	NP_511166.2	Gene:	mRpL3 / 32523	FlyBaseID:	FBgn0030686	Length:	362	Species:	Drosophila melanogaster
Sequence 2:	NP_001100322.1	Gene:	Mrpl3 / 300974	RGDID:	1306391	Length:	348	Species:	Rattus norvegicus

Alignment Length:	323	Identity:	132/323 - (40%)
Similarity:	183/323 - (56%)	Gaps:	27/323 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 KEITKYNDLMTAENKQFVNE-VGTNNFGVPAVIKDSLVKTAGPTANEA----VWTPNLRRCGVIA 104
            |..|.:::.::.||..||.: |...|       |..|.....|..:|.    .|.|...|.|:||
  Rat    44 KSSTWWDEHLSEENVSFVKQLVSDEN-------KAQLTSKLNPLKDEPWPLHPWEPGSSRVGLIA 101

  Fly   105 RKIGQYPLWLKNGERIRTTLLQIVDNHVIKYIPPEEYLPAQVPTVANLHKRGCILVGSETTNPAL 169
            .|:|..|||.|:|::...||||:.|.||:||.|.|::          ..|...:.||.:|.:...
  Rat   102 LKLGMMPLWTKDGQKHAVTLLQVQDCHVLKYTPKEDH----------NGKTAALTVGGKTGSRLY 156

  Fly   170 LTKEYAGIFRNSGVLPKKNLARFIVSPEAQLAPGTPLNVNHFRVGDFVDVRGKTVDHGFQGVVKR 234
            ........:|:.|:.||:.:..|.|:..|.:.|||||...|||.|.:|||..||:..|||||:||
  Rat   157 KPNSILEFYRDLGLPPKQTIKIFHVTDNAVIKPGTPLYAAHFRPGQYVDVTAKTIGKGFQGVMKR 221

  Fly   235 HGFKGMPASHGVTKTHRRAGNIGGGGEKGRVWPGTKMPGHMGNRWRIIKGLRVWRINTKYNVMWV 299
            .||||.|||||.||||||.|.| ..|:..||||||||||.|||:.|.:.||:|||:|||:|:::|
  Rat   222 WGFKGQPASHGQTKTHRRPGAI-STGDIARVWPGTKMPGQMGNQNRTVYGLKVWRVNTKHNIIYV 285

  Fly   300 QGSSVAGPTGGLVYIYDTILPTRKNK-EAPPFPTFY--GEPQQDGDDVWYEQVHNFKSESITY 359
            .| ||.|....||.|.|:.||..|:. ::.||||::  |:.::..:|::.|.|......|||:
  Rat   286 NG-SVPGHRNCLVKIKDSTLPAYKDLCKSLPFPTYFPDGDEEELPEDLYDESVWQPSEPSITF 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mRpL3	NP_511166.2	RplC	101..314	CDD:294230	101/212 (48%)
Mrpl3	NP_001100322.1	rplC	96..302	CDD:234564	103/217 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341647
Domainoid	1	1.000	124	1.000	Domainoid score	I5399
eggNOG	1	0.900	-	-		E1_COG0087
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H31431
Inparanoid	1	1.050	217	1.000	Inparanoid score	I3507
OMA	1	1.010	-	-		QHG55656
OrthoDB	1	1.010	-	-		D1269775at2759
OrthoFinder	1	1.000	-	-		FOG0003599
OrthoInspector	1	1.000	-	-		oto97368
orthoMCL	1	0.900	-	-		OOG6_100949
Panther	1	1.100	-	-	LDO	PTHR11229
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2474
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770