Protein Alignment CG8260 and Klhl35

DIOPT Version :10

• Sequence 1: NP_573069.1
• Gene: CG8260 / 32521
• FlyBaseID: FBgn0030684
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: XP_006508283.1
• Gene: Klhl35 / 72184
• MGIID: 1919434
• Length: 579
• Species: Mus musculus
• Alignment Length: 253
• Identity: 53/253 - (20%)
• Similarity: 95/253 - (37%)
• Gaps: 32/253 - (12%)

  Fly    65 KEDP-TESEIVEIDHEVPPEEYLVPYIQNYECADIIVTVHDRVFLCHNIILSIYSRRMLKILQED 128
            :|:| ||:......|.....:.|..|.::....|:::....|.|.||...||..|.....:....
Mouse     8 EEEPGTEAPCAASCHAQRILQTLNAYRRSGTLTDVVLRAGGRDFPCHRAALSAASAHFRGLFAAG 72

  Fly   129 VDHIVFKSNDLSPK--GFSDA------YLW----MISSDGEVNPCDMGEILRAAYFLDIPELLEA 181
            ..........:.|:  |.:.|      |::    .:.::.|.     ..:|..|..|.:..|.||
Mouse    73 RPERAAAVVPVGPETPGTAAALAVVLDYVYGAGVRLRAEDEA-----AAVLALAERLGVAGLREA 132

  Fly   182 CWANLD-RITFFEISAFRLLFELRGATNLWDVFDKLTGRISISILPVASTREFLCLSETQICYIL 245
            |...|: |:......|.|   .:..|.:|..:.::....:..:.:.|....:||.|:..::..:|
Mouse   133 CARFLEGRLRAANSLALR---RVAAAFSLASLAERCGRVLRQAFVEVTRHADFLELAPDEVAALL 194

  Fly   246 KSNFLAINSE---MEAS------SISIRRSSTYRVLSQIRFSFL-PPLMLKKFRSEEL 293
            ....|.:..|   .||:      ....||....|:|..:|...| |...|:|..::||
Mouse   195 ADPALRVAREEAVFEAAMRWVRHDAPARRGQLRRLLEHVRLPLLAPAYFLEKVEADEL 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8260	NP_573069.1	BTB_POZ	97..186	CDD:453885	20/100 (20%)
		BACK	200..287	CDD:197943	19/96 (20%)
		DUF4734	305..387	CDD:434992
Klhl35	XP_006508283.1	BTB_POZ_KLHL35	17..148	CDD:349574	25/135 (19%)
		BACK	<171..254	CDD:475122	20/82 (24%)
		NanM	293..511	CDD:442289
		KELCH repeat	331..371	CDD:276965
		KELCH repeat	375..419	CDD:276965
		KELCH repeat	422..467	CDD:276965
		KELCH repeat	470..510	CDD:276965