Protein Alignment CG8260 and Klhl5

DIOPT Version :10

• Sequence 1: NP_573069.1
• Gene: CG8260 / 32521
• FlyBaseID: FBgn0030684
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_780383.2
• Gene: Klhl5 / 71778
• MGIID: 1919028
• Length: 708
• Species: Mus musculus
• Alignment Length: 291
• Identity: 60/291 - (20%)
• Similarity: 110/291 - (37%)
• Gaps: 43/291 - (14%)

  Fly    58 ANSIRTLKE----DPTESE--IVEIDHEVPPEEYLVPYIQNYECADIIVTVHDRVFLCHNIILSI 116
            :||.:||..    :|..|:  ...::|.....:.:..|:::.:..|:|:...||....|.::||.
Mouse   129 SNSSQTLSSCQAMEPCSSDEFFQALNHAEQTFKKMENYLRHKQLCDVILVAGDRRIPAHRLVLSS 193

  Fly   117 YSRRMLKILQEDVDHIVFKSNDLSPKGFSDAYLWMISSDGEVNPCDMGE-----ILRAAYFLDIP 176
            .|.....:...||...  :..::..:|.....||.:.........::.|     :|..|..|.:.
Mouse   194 VSDYFAAMFTNDVREA--RQEEIKMEGVEPNSLWSLIQYAYTGRLELKEDNIECLLSTACLLQLS 256

  Fly   177 ELLEACWANL-DRITFFEISAFRLLFELRGATNLWDVFDKLTGRISISILPVASTREFLCLSETQ 240
            :::|||...| .::........|...:.:|.|:|..|....|..   ..:.|...:||:.|...:
Mouse   257 QVVEACCKFLMKQLHPSNCLGIRSFADAQGCTDLHKVAHNYTME---HFMEVIRNQEFVLLPANE 318

  Fly   241 ICYILKSNFLAINSE---MEA------SSISIRRSSTYRVLSQIRFSFLPPLMLKKFRSEEL--- 293
            |..:|.|:.:.|.:|   :.|      ..:..||....|:|:.||...|.|..|....:..|
Mouse   319 IAKLLASDDMNIPNEETILNALLTWVRHDLEQRRKDLSRLLAYIRLPLLAPQFLADMENNALFRD 383

  Fly   294 --------------HKMPEFSDILKEFSKSP 310
                          |.:||...:|:.....|
Mouse   384 DIECQKLIMEAMKYHLLPERRPMLQSPRTKP 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8260	NP_573069.1	BTB_POZ	97..186	CDD:453885	20/93 (22%)
		BACK	200..287	CDD:197943	24/95 (25%)
		DUF4734	305..387	CDD:434992	1/6 (17%)
Klhl5	NP_780383.2	PHA03098	173..695	CDD:222983	52/247 (21%)
		KELCH repeat	457..500	CDD:276965
		KELCH repeat	504..548	CDD:276965
		KELCH repeat	551..594	CDD:276965
		KELCH repeat	598..648	CDD:276965
		KELCH repeat	651..694	CDD:276965