Protein Alignment CG8260 and KLHL18

DIOPT Version :10

• Sequence 1: NP_573069.1
• Gene: CG8260 / 32521
• FlyBaseID: FBgn0030684
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_650143.1
• Gene: KLHL18 / 41458
• FlyBaseID: FBgn0037978
• Length: 575
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 60/286 - (20%)
• Similarity: 114/286 - (39%)
• Gaps: 35/286 - (12%)

  Fly    97 DIIVTVHDRVFLCHNIILS-----IYSRRMLKILQEDVDHIVFKSNDLSPKGFSDAYLWMISSDG 156
            |:.:.|.|:.|..|.::|:     .|:.....:.:..:..|..|.:.:.|........::.|...
  Fly    40 DVTLKVEDQTFSAHRVVLAATIPYFYAMFTNNMAESRIKEITMKESAIEPSALESLINYVYSGQV 104

  Fly   157 EVNPCDMGEILRAAYFLDIPELLEACWANL-DRITFFEISAFRLLFELRGATNLWDVFDKLTGRI 220
            .::..::..::..|.||.:..:.:||.:.| .|.....:...|...:......|.|..||.   |
  Fly   105 RIDNQNVQNLMVGASFLQLSNVRDACASFLISRFHPHNVLGIRTFADSMICRQLIDAADKY---I 166

  Fly   221 SISILPVASTREFLCLSETQICYILKSNFLAINSE---MEASSISI-----RRSSTY-RVLSQIR 276
            ..:...|:.:.|||.|...|:..:::.:.|.:.:|   .||....:     :||..: :||:.:|
  Fly   167 DQNFAKVSQSEEFLALDCEQLLELMRRDELNVRTEEVIFEACMKWVKYAEDKRSELFPQVLAAVR 231

  Fly   277 FSFLPPLML-KKFRSEEL----HKMPEFSDILKEFSKSPDVITLL-------RDSVFNSSLLLTV 329
            ...|.|..| .:...|||    |:..:..|..|:|...|:...||       |...|.:..:..|
  Fly   232 LPLLSPQFLADRVAREELIRSSHQCRDLLDEAKDFHLMPERRGLLQSFRTRQRSGEFFTGQIYAV 296

  Fly   330 RNNPSVLDTHVEFTEVELMEP--RHW 353
               ..:..|....:.||:.:|  :.|
  Fly   297 ---GGLASTGESVSTVEIYDPLTKKW 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8260	NP_573069.1	BTB_POZ	97..186	CDD:453885	16/93 (17%)
		BACK	200..287	CDD:197943	23/96 (24%)
		DUF4734	305..387	CDD:434992	12/58 (21%)
KLHL18	NP_650143.1	BTB_POZ_KLHL18	20..137	CDD:349556	17/96 (18%)
		PHA03098	36..510	CDD:222983	60/286 (21%)
		KELCH repeat	329..372	CDD:276965
		KELCH repeat	376..417	CDD:276965
		KELCH repeat	423..466	CDD:276965
		KELCH repeat	470..514	CDD:276965
		Kelch_1	517..560	CDD:396078
		KELCH repeat	517..560	CDD:276965