Protein Alignment CG8260 and Klhl4

DIOPT Version :10

• Sequence 1: NP_573069.1
• Gene: CG8260 / 32521
• FlyBaseID: FBgn0030684
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_001101714.1
• Gene: Klhl4 / 317196
• RGDID: 1565441
• Length: 717
• Species: Rattus norvegicus
• Alignment Length: 291
• Identity: 52/291 - (17%)
• Similarity: 108/291 - (37%)
• Gaps: 51/291 - (17%)

  Fly    62 RTLKEDPTESEIVEIDH--EVPPEEY----LVPYIQNYECADIIVTVHDRVFLCHNIILS----- 115
            |...|:|.:..::..||  .....:|    :..|::..:..|:::.........|.::||
  Rat   141 RQYAEEPEQMNVISEDHYRSRNHADYTLCKMESYLKEKKLCDVLLIAGPLKIPAHRLVLSAVSDY 205

  Fly   116 ---IYSRRMLKILQEDVDHIVFKSNDLSPKGFSDAYLWMISSDGEVNPCDMGEILRAAYFLDIPE 177
               :::..:|:..||:|     |...:.|...:....:..:...::....:..:|.||..|.:.:
  Rat   206 FAAMFTNDVLEARQEEV-----KMEGVDPNALNSLVQYAYTGVLQLREDTIENLLSAACLLQLTQ 265

  Fly   178 LLEACWAN--LDRITFFEISAFRLLFELRGATNLWDVFDKLTGRISISILPVASTREFLCLSETQ 240
            :::.| .|  :.::........|...:.:|...|.:|..|.|..   ..:.|...:|||.|...:
  Rat   266 VIDVC-CNFLIKQLHPSNCLGIRSFGDAQGCMELQNVAHKYTME---HFIDVVKNQEFLLLPANE 326

  Fly   241 ICYILKSNFLAINSE-------ME--ASSISIRRSSTYRVLSQIRFSFLPPLMLKKFRSEEL--- 293
            |..:|.|:.:.:..|       |:  ......|:....::||.||...|.|.:|....:..:
  Rat   327 ISKLLCSDDINVPDEETIFHALMQWVGHDAQARQQDLAKLLSYIRLPLLSPQLLADLENSSMFSG 391

  Fly   294 --------------HKMPEFSDILKEFSKSP 310
                          |.:||...:|:.....|
  Rat   392 DLECQKLLMEAMKYHLLPERRSMLQSPRTKP 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8260	NP_573069.1	BTB_POZ	97..186	CDD:453885	16/98 (16%)
		BACK	200..287	CDD:197943	23/95 (24%)
		DUF4734	305..387	CDD:434992	1/6 (17%)
Klhl4	NP_001101714.1	PHA03098	175..697	CDD:222983	45/257 (18%)
		KELCH repeat	465..508	CDD:276965
		KELCH repeat	512..556	CDD:276965
		KELCH repeat	559..602	CDD:276965
		KELCH repeat	606..657	CDD:276965
		KELCH repeat	659..698	CDD:276965