Protein Alignment CG8260 and Klhl5

DIOPT Version :10

• Sequence 1: NP_573069.1
• Gene: CG8260 / 32521
• FlyBaseID: FBgn0030684
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_001040558.1
• Gene: Klhl5 / 305351
• RGDID: 1309661
• Length: 708
• Species: Rattus norvegicus
• Alignment Length: 291
• Identity: 58/291 - (19%)
• Similarity: 110/291 - (37%)
• Gaps: 43/291 - (14%)

  Fly    58 ANSIRTLKE----DPTESE--IVEIDHEVPPEEYLVPYIQNYECADIIVTVHDRVFLCHNIILSI 116
            :||.:||..    :|..|:  ...::|.....:.:..|:::.:..|:|:...||....|.::||.
  Rat   129 SNSSQTLSSCQTMEPCSSDEFFQALNHAEQTFKKMENYLRHKQLCDVILVAGDRRIPAHRLVLSS 193

  Fly   117 YSRRMLKILQEDVDHIVFKSNDLSPKGFSDAYLWMISSDGEVNPCDMGE-----ILRAAYFLDIP 176
            .|.....:...||...  :..::..:|.....||.:.........::.|     :|..|..|.:.
  Rat   194 VSDYFAAMFTNDVREA--RQEEIKMEGVEPNSLWSLIQYAYTGRLELKEENIECLLSTACLLQLS 256

  Fly   177 ELLEACWANL-DRITFFEISAFRLLFELRGATNLWDVFDKLTGRISISILPVASTREFLCLSETQ 240
            :::|||...| .::........|...:.:|.|:|..|....|..   ..:.|...:||:.|...:
  Rat   257 QVVEACCKFLMKQLHPSNCLGIRSFADAQGCTDLHKVAHNYTME---HFMEVIRNQEFVLLPANE 318

  Fly   241 ICYILKSNFLAINSE---MEA------SSISIRRSSTYRVLSQIRFSFLPPLMLKKFRSEEL--- 293
            |..:|.|:.:.|.:|   :.|      ..:..|:....::|:.||...|.|..|....:..|
  Rat   319 IAKLLASDDMNIPNEETILNALLTWVRHDLEQRQKDLSKLLAYIRLPLLAPQFLADMENNALFRD 383

  Fly   294 --------------HKMPEFSDILKEFSKSP 310
                          |.:||...:|:.....|
  Rat   384 DIECQKLIMEAMKYHLLPERRPMLQSPRTKP 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8260	NP_573069.1	BTB_POZ	97..186	CDD:453885	20/93 (22%)
		BACK	200..287	CDD:197943	22/95 (23%)
		DUF4734	305..387	CDD:434992	1/6 (17%)
Klhl5	NP_001040558.1	PHA03098	173..695	CDD:222983	50/247 (20%)
		KELCH repeat	457..500	CDD:276965
		KELCH repeat	504..548	CDD:276965
		KELCH repeat	551..594	CDD:276965
		KELCH repeat	598..648	CDD:276965
		KELCH repeat	651..694	CDD:276965