Protein Alignment CG8260 and Klhl4

DIOPT Version :10

• Sequence 1: NP_573069.1
• Gene: CG8260 / 32521
• FlyBaseID: FBgn0030684
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_766369.2
• Gene: Klhl4 / 237010
• MGIID: 2442829
• Length: 717
• Species: Mus musculus
• Alignment Length: 258
• Identity: 47/258 - (18%)
• Similarity: 98/258 - (37%)
• Gaps: 45/258 - (17%)

  Fly    89 YIQNYECADIIVTVHDRVFLCHNIILS--------IYSRRMLKILQEDVDHIVFKSNDLSPKGFS 145
            |::..:..|:::.........|.::||        :::..:|:..||:|     |...:.|...:
Mouse   174 YLKERKLCDVLLIAGPLKIPAHRLVLSAVSDYFAAMFTNDVLEARQEEV-----KIEGVDPNALN 233

  Fly   146 DAYLWMISSDGEVNPCDMGEILRAAYFLDIPELLEACWAN--LDRITFFEISAFRLLFELRGATN 208
            ....:..:...::....:..:|.||..|.:.::::.| .|  :.::........|...:.:|...
Mouse   234 SLVQYAYTGVLQLREDTIENLLSAACLLQLTQVIDVC-CNFLIKQLHPSNCLGIRSFGDAQGCME 297

  Fly   209 LWDVFDKLTGRISISILPVASTREFLCLSETQICYILKSNFLAINSE-------ME--ASSISIR 264
            |.:|..|......|.::   ..:|||.|...:|..:|.|:.:.:..|       |:  ......|
Mouse   298 LQNVAHKYAMEHFIDVI---KNQEFLLLPANEISKLLCSDDINVPDEETIFHALMQWVGHDAQAR 359

  Fly   265 RSSTYRVLSQIRFSFLPPLML---------------KKFRSEEL--HKMPEFSDILKEFSKSP 310
            :....::||.||...|.|.:|               :|...|.:  |.:||...:|:.....|
Mouse   360 QRDLAKLLSYIRLPLLSPQLLADLENSSFFSGNLECQKLLMEAMKYHLLPERRSMLQSPRTKP 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8260	NP_573069.1	BTB_POZ	97..186	CDD:453885	16/98 (16%)
		BACK	200..287	CDD:197943	22/110 (20%)
		DUF4734	305..387	CDD:434992	1/6 (17%)
Klhl4	NP_766369.2	PHA03098	175..697	CDD:222983	46/257 (18%)
		KELCH repeat	465..508	CDD:276965
		KELCH repeat	512..556	CDD:276965
		KELCH repeat	559..602	CDD:276965
		KELCH repeat	606..657	CDD:276965
		KELCH repeat	659..698	CDD:276965