Protein Alignment CG8260 and Klhl41

DIOPT Version :10

• Sequence 1: NP_573069.1
• Gene: CG8260 / 32521
• FlyBaseID: FBgn0030684
• Length: 415
• Species: Drosophila melanogaster
• Sequence 2: NP_001074556.1
• Gene: Klhl41 / 228003
• MGIID: 2683854
• Length: 606
• Species: Mus musculus
• Alignment Length: 270
• Identity: 60/270 - (22%)
• Similarity: 108/270 - (40%)
• Gaps: 64/270 - (23%)

  Fly    83 EEYLVPYIQNYECADIIVTVHDRVFLCHNIILS-------------IYSRRMLKILQEDVDHIVF 134
            ::.|...::..:..|..:...|:.|.||.:|||             |...:..::..::||..:.
Mouse    20 QDGLKDLLEEKKFIDCTLKAGDKSFPCHRLILSACSPYFREYFLSEIEEEKKKEVALDNVDPAIL 84

  Fly   135 KSNDLSPKGFSDAYLWMISSDGEVNPCDMGEILRAAYFLDIPELLEACWANLDRITFFEISAFRL 199
               ||..|     ||:..|.|  :|..::.:|...:....||.:...|.:.|.:    .::....
Mouse    85 ---DLIIK-----YLYSASID--LNDGNVQDIFALSSRFQIPSVFTVCVSYLQK----RLAPGNC 135

  Fly   200 LFELRGATNLWDVFDKLTGRISISILPVASTR--------EFLCLSETQICYILKSNFLAINSE- 255
            |..||    |..:.|  ..|::||.....|.|        :|:.||..::..::.::.|.:..|
Mouse   136 LAILR----LGLLLD--CPRLAISAREFVSDRFVQICKEEDFMQLSPQELISVISNDSLNVEKEE 194

  Fly   256 --MEASSISIRRSSTYR------VLSQIRFSFLPPLMLKKFRSEELHKMPEFSDILKEFSKSPDV 312
              .||....:|.....|      |...|||.    ||.:|:..:.:.|    .||:|   .:|:|
Mouse   195 VVFEAVMKWVRTDKENRAKNLSEVFDCIRFR----LMAEKYFKDHVEK----DDIIK---SNPEV 248

  Fly   313 ---ITLLRDS 319
               |.:|:|:
Mouse   249 QKKIKVLKDA 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8260	NP_573069.1	BTB_POZ	97..186	CDD:453885	23/101 (23%)
		BACK	200..287	CDD:197943	25/103 (24%)
		DUF4734	305..387	CDD:434992	5/18 (28%)
Klhl41	NP_001074556.1	BTB_POZ_KLHL41_KBTBD10	6..135	CDD:349650	25/128 (20%)
		PHA03098	39..578	CDD:222983	58/251 (23%)
		KELCH repeat	335..384	CDD:276965
		Kelch 1	346..398
		KELCH repeat	388..433	CDD:276965
		Kelch 2	399..447
		KELCH repeat	437..482	CDD:276965
		Kelch 3	448..495
		KELCH repeat	485..530	CDD:276965
		Kelch 4	497..542
		Kelch 5	544..599