DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mvd and mvd1

DIOPT Version :9

Sequence 1:	NP_001285295.1	Gene:	Mvd / 32520	FlyBaseID:	FBgn0030683	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_594027.1	Gene:	mvd1 / 2541430	PomBaseID:	SPAC24C9.03	Length:	393	Species:	Schizosaccharomyces pombe

Alignment Length:	386	Identity:	175/386 - (45%)
Similarity:	241/386 - (62%)	Gaps:	14/386 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFSVTCVAPVNIALIKYWGKRHEELILPVNDSISMTLSTDELCAKTTVTASESFETNRMWLNGEE 65
            ::..|..||||||:|||||||...|.||.|.|||:|||.|:|...||.:.||.||.:.:||||..
pombe     5 VYQCTVSAPVNIAVIKYWGKRDVALNLPTNSSISVTLSQDDLRTVTTASCSEKFENDTLWLNGNA 69

  Fly    66 VPFEESSRLQRCLNEVH--RLAVASGSQKVPP--TWKLHIASVNNFPTAAGLASSAAGYACLVYS 126
            .....:.||:.|:.|:.  ||.:...:..:..  ..|||:.|.|||||||||||||||||....:
pombe    70 EEIFANKRLRVCVEELRKARLDLEEENDDLDKIGALKLHVVSENNFPTAAGLASSAAGYAAFCEA 134

  Fly   127 LSRLYDIPLN-EELTTVARQGSGSACRSLYGGFVQWHRGALDDGSDSVARQIAPSDHWPNMHVLI 190
            ::||||:|.. .:|:.:||||||||||||:||:|.|..|.|..|:||||.|:.|.::||.:.|.:
pombe   135 IARLYDLPWTPTQLSRIARQGSGSACRSLFGGYVAWEMGELHSGADSVAVQVEPVENWPEIRVAV 199

  Fly   191 LVVNDARKKTASTRGMQQAVKTSQLIKHRVDQVVPDRIIRLREAIASHDFQAFAEITMKDSNQFH 255
            ||.:.|:|..:||.|||..|.:|.|.:||:..:||.||..::.||...||:.||::||.||||||
pombe   200 LVASAAKKGVSSTAGMQATVASSTLFQHRIQNIVPQRIQEMKTAIRERDFETFAKLTMTDSNQFH 264

  Fly   256 AIALDTYPPCVYMNDVSHSIVSFVHDYNERMGSYHAAYTFDAGPNACLYVLAEHVPHLLSAIQKV 320
            |..|||:||..|:||.|.:::..|.:.|...|...|||||||||||.:|.|.|:...:|:.:..|
pombe   265 ACCLDTFPPIFYLNDTSRAVIRVVENINATAGKTIAAYTFDAGPNAVIYFLEENSEIVLNTLYAV 329

  Fly   321 FPNDLADGGTYLRGLPIPKVQDAESSKLDSLDVHAKNAFRYIIHTKVGEGPKELSADNSLL 381
            ..|  |:|.:...| ..|...|:.::.:.|      :....:|.|:||.||:.|:.|.||:
pombe   330 TKN--AEGWSKQYG-SSPVTVDSAAANIVS------SGISRVILTRVGNGPRVLTIDESLI 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mvd	NP_001285295.1	PLN02407	1..322	CDD:178029	158/325 (49%)
Mvd	NP_001285295.1	GHMP_kinases_C	231..323	CDD:285715	43/91 (47%)
mvd1	NP_594027.1	PLN02407	5..316	CDD:178029	154/310 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	136	1.000	Domainoid score	I1259
eggNOG	1	0.900	-	-		E1_COG3407
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1843
Inparanoid	1	1.050	322	1.000	Inparanoid score	I546
OMA	1	1.010	-	-		QHG62270
OrthoFinder	1	1.000	-	-		FOG0004204
OrthoInspector	1	1.000	-	-		oto101437
orthoMCL	1	0.900	-	-		OOG6_102327
Panther	1	1.100	-	-	LDO	PTHR10977
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R783
SonicParanoid	1	1.000	-	-		X2949
TreeFam	1	0.960	-	-
	14	13.860