Protein Alignment CCT6 and CCT2

DIOPT Version :10

• Sequence 1: NP_573066.1
• Gene: CCT6 / 32518
• FlyBaseID: FBgn0027329
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_012124.1
• Gene: CCT2 / 854664
• SGDID: S000001404
• Length: 527
• Species: Saccharomyces cerevisiae
• Alignment Length: 533
• Identity: 149/533 - (27%)
• Similarity: 272/533 - (51%)
• Gaps: 26/533 - (4%)

  Fly     3 SISLLNPKAEFARAAQALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGD-IKITKDGNVLLHE 66
            |:.:...:....||..|.......|..:.|::::.|||||..|:|.|.:.: ..:|.||..:|..
Yeast     2 SVQIFGDQVTEERAENARLSAFVGAIAVGDLVKSTLGPKGMDKLLQSASSNTCMVTNDGATILKS 66

  Fly    67 MQIQHPTASMIARASTAQDDSTGDGTTTTVMLIGELLKQADIYLSEG-LHPRIMTDGFEKARDKA 130
            :.:.:|.|.::...|..|||..|||||:..:|..|||::|:..:.:. :||:.:.:|:..|...|
Yeast    67 IPLDNPAAKVLVNISKVQDDEVGDGTTSVTVLSAELLREAEKLIDQSKIHPQTIIEGYRLASAAA 131

  Fly   131 LEVLDQVKVPVEINK----KNLVEVANTSLKTKVHPALADLLTDVCVNAVLTIASADKTKPVDLH 191
            |:.|.:..|....:|    ::|:.:|.|:|.:|:.....|...::..||:|.:..:     .:|.
Yeast   132 LDALTKAAVDNSHDKTMFREDLIHIAKTTLSSKILSQDKDHFAELATNAILRLKGS-----TNLE 191

  Fly   192 MVELMEMQHKSDTDTQLVRGLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEV-NSGFFYKTA 255
            .::::::.....:|:.|..|.::.....: :.|||:|||.||.||.:|:.:|.:: .:.|...:.
Yeast   192 HIQIIKILGGKLSDSFLDEGFILAKKFGN-NQPKRIENAKILIANTTLDTDKVKIFGTKFKVDST 255

  Fly   256 EEREAFVRAEREFIDQRVKKVIELKRSVCDGTDKTFVLINQKGIDPISLDALAKEGILALRRAKR 320
            .:.....:||||.:..::.|:.:.      |.: ||  ||::.|...........||.::..|..
Yeast   256 AKLAQLEKAEREKMKNKIAKISKF------GIN-TF--INRQLIYDYPEQLFTDLGINSIEHADF 311

  Fly   321 RNMERLSLACGGTAMNSFDDLQEEHLGYAGVVYEHVLGENKYTFVEDCKNPLSVTILIKGPNKHT 385
            ..:|||:|..||..:::||:..:..||...|:.|.:|||..:.....||...:.||:::|....|
Yeast   312 EGVERLALVTGGEVVSTFDEPSKCKLGECDVIEEIMLGEQPFLKFSGCKAGEACTIVLRGATDQT 376

  Fly   386 ITQIKDAIRDGLRAINNTIADKALVPGAGAFEVRAYNELVAFKDTIKGKSRLAVQAFADALLVIP 450
            :.:.:.::.|.|..::.|..:...|.|.|..|:.....:......|.||..|||:|||.||..:|
Yeast   377 LDEAERSLHDALSVLSQTTKETRTVLGGGCAEMVMSKAVDTEAQNIDGKKSLAVEAFARALRQLP 441

  Fly   451 KTLAVNSGYDAQDTIVKL--TVEDRLSPELVGLDLATGEPMKPVDLGVYDNYIVKKQILNSCSII 513
            ..||.|:|:|:.:.:.||  ::.:.:|..  ||||..|.......||:.::|.:|:.:::|.|..
Yeast   442 TILADNAGFDSSELVSKLRSSIYNGISTS--GLDLNNGTIADMRQLGIVESYKLKRAVVSSASEA 504

  Fly   514 ASNLLLVDEVMRA 526
            |..||.||.::||
Yeast   505 AEVLLRVDNIIRA 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	TCP1_zeta	7..528	CDD:239458	148/529 (28%)
CCT2	NP_012124.1	TCP1_beta	5..520	CDD:239452	148/530 (28%)