Protein Alignment CCT6 and HSP60

DIOPT Version :10

• Sequence 1: NP_573066.1
• Gene: CCT6 / 32518
• FlyBaseID: FBgn0027329
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_013360.1
• Gene: HSP60 / 850963
• SGDID: S000004249
• Length: 572
• Species: Saccharomyces cerevisiae
• Alignment Length: 588
• Identity: 123/588 - (20%)
• Similarity: 224/588 - (38%)
• Gaps: 132/588 - (22%)

  Fly    25 SAAKG---LQDVMRTNLGPKGTVKMLVSGAGDIKITKDG-----NVLLHEMQIQHPTASMIARAS 81
            |..||   |.:.:...|||||...::....|..||||||     :::|.: :.::..|.::...:
Yeast    36 SLLKGVETLAEAVAATLGPKGRNVLIEQPFGPPKITKDGVTVAKSIVLKD-KFENMGAKLLQEVA 99

  Fly    82 TAQDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKALEVLDQVKVPVEINKK 146
            :..:::.|||||:..:|...:..::...::.|.:|..:..|.:.|.:|.:|.|...|..:..:::
Yeast   100 SKTNEAAGDGTTSATVLGRAIFTESVKNVAAGCNPMDLRRGSQVAVEKVIEFLSANKKEITTSEE 164

  Fly   147 NLVEVANTSLKTKVH--PALADLLTDVCVNAVLTIASADKTKPVDLHMVELMEMQHKSDTDTQLV 209
             :.:||..|.....|  ..||..:..|....|:||... :|...:|.:.|
Yeast   165 -IAQVATISANGDSHVGKLLASAMEKVGKEGVITIREG-RTLEDELEVTE--------------- 212

  Fly   210 RGLVMDHGARHPDMPKRLENAYILT--ANVSLEYEKAEVNSGFFYKTAEEREAFVR---AEREFI 269
             |:..|.|...|         |.:|  .:..:|:||.      ....:|::.:.::   ...|..
Yeast   213 -GMRFDRGFISP---------YFITDPKSSKVEFEKP------LLLLSEKKISSIQDILPALEIS 261

  Fly   270 DQRVKKVIELKRSVCDGTDKTFVLINQ-KGIDPISLDALAKEGILALRRAKRRN-MERLSLACGG 332
            :|..:.::.:...| ||......::|: :|  .:.:.|:...|.    ...|:| :..:::..||
Yeast   262 NQSRRPLLIIAEDV-DGEALAACILNKLRG--QVKVCAVKAPGF----GDNRKNTIGDIAVLTGG 319

  Fly   333 TAMNSFDDLQE-----EHLGYA--------------GVVYEHVLGENKYTFVEDCKNPLSVT--- 375
            |......||:.     |:||..              |...:..:.|.    :|..|..:.:|
Yeast   320 TVFTEELDLKPEQCTIENLGSCDSITVTKEDTVILNGSGPKEAIQER----IEQIKGSIDITTTN 380

  Fly   376 --------------------ILIKGPNKHTITQIKDAIRDGLRAINNTIADKALVPGAGAFEVRA 420
                                |.:.|.::..:.:.||...|.|.|....: ::.::||.|...|:|
Yeast   381 SYEKEKLQERLAKLSGGVAVIRVGGASEVEVGEKKDRYDDALNATRAAV-EEGILPGGGTALVKA 444

  Fly   421 ---YNELVAFKDTIKGKSRLAVQAFADALLVIPKTLAVNSGYDAQDTIVKLTVEDRLSPELV-GL 481
               .:|:|.  |....|  |.|.....|:....|.:..|:|.:....|.||.  |....:.. |.
Yeast   445 SRVLDEVVV--DNFDQK--LGVDIIRKAITRPAKQIIENAGEEGSVIIGKLI--DEYGDDFAKGY 503

  Fly   482 DLATGEPMKPVDLGVYDNYIVKKQILNSCSIIASNLLLVDEV----------------MRAGMTS 530
            |.:..|....:..|:.|.:.|.:..|...|.:|| ||...||                |..||..
Yeast   504 DASKSEYTDMLATGIIDPFKVVRSGLVDASGVAS-LLATTEVAIVDAPEPPAAAGAGGMPGGMPG 567

  Fly   531 LKG 533
            :.|
Yeast   568 MPG 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	TCP1_zeta	7..528	CDD:239458	120/581 (21%)
HSP60	NP_013360.1	GroEL	25..548	CDD:239460	119/564 (21%)