Protein Alignment CCT6 and MKKS

DIOPT Version :9

• Sequence 1: NP_573066.1
• Gene: CCT6 / 32518
• FlyBaseID: FBgn0027329
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_061336.1
• Gene: MKKS / 8195
• HGNCID: 7108
• Length: 570
• Species: Homo sapiens
• Alignment Length: 506
• Identity: 96/506 - (18%)
• Similarity: 167/506 - (33%)
• Gaps: 145/506 - (28%)

  Fly    30 LQDVMRTNLGPKGTVKMLVSG-AGDIKITKDGNVLLHEMQIQHP-----TASMIARASTAQD--- 85
            |:.::.:..||.|.:|.|.:| .|.:..|...:.||..:.:.||     |||:....|:..|
Human    29 LKRIVTSCYGPSGRLKQLHNGFGGYVCTTSQSSALLSHLLVTHPILKILTASIQNHVSSFSDCGL 93

  Fly    86 -------------DSTGDGTTTTVMLIGELLKQADIYL-SEGLHPRIMTDGFEKARDKALEVLDQ 136
                         ...|...||.:.|...||.....|| ||       |.|
Human    94 FTAILCCNLIENVQRLGLTPTTVIRLNKHLLSLCISYLKSE-------TCG-------------- 137

  Fly   137 VKVPVEINKKNLVEVANTSLKTKVHPALADLLTDVC-VNAVLTIASADKTKPVDLHMVELMEMQH 200
            .::||:.:...::                     :| |.::||      :||.  .|:...|.:|
Human   138 CRIPVDFSSTQIL---------------------LCLVRSILT------SKPA--CMLTRKETEH 173

  Fly   201 KSDTDTQLVRGLVMDHGARHPDMPKRLENAYIL----------------TANVSLEYEKAEVN-- 247
            .|   ..::|..::       .:|:..|...||                |....:..|.:||.
Human   174 VS---ALILRAFLL-------TIPENAEGHIILGKSLIVPLKGQRVIDSTVLPGILIEMSEVQLM 228

  Fly   248 --------------------SGFFYKTAEEREAF---VRAEREFIDQRVKKVIELKRSVCDGTDK 289
                                ||....|.|.....   |..|...:||    ::.|.|.:.  :|.
Human   229 RLLPIKKSTALKVALFCTTLSGDTSDTGEGTVVVSYGVSLENAVLDQ----LLNLGRQLI--SDH 287

  Fly   290 TFVLINQKGIDPISLDALAKEGILALRRAKRRNMERLSLACGGTAMNSFDDLQEEHLGYAGVVYE 354
            ..:::.||.|.|.....|....|:|:.|.....||.|:...|...:.|...:.....|....|..
Human   288 VDLVLCQKVIHPSLKQFLNMHRIIAIDRIGVTLMEPLTKMTGTQPIGSLGSICPNSYGSVKDVCT 352

  Fly   355 HVLGENKYTFVEDCKNPLSV-TILIKGPNKHTITQIKDAIRDGLRAINNTIADKALVPGAGAFEV 418
            ...|...  |.....|..:: ::|:...|.....::|...:..|..:..|:.:...:.|.|..|.
Human   353 AKFGSKH--FFHLIPNEATICSLLLCNRNDTAWDELKLTCQTALHVLQLTLKEPWALLGGGCTET 415

  Fly   419 --------RAYNE---LVAFKDTIKGKSRLAVQAFADALLVIPKTLAVNSG 458
                    :.:|:   ::...:..:.:.:|..:||..||..:..:|..:.|
Human   416 HLAAYIRHKTHNDPESILKDDECTQTELQLIAEAFCSALESVVGSLEHDGG 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	chap_CCT_zeta	3..532	CDD:274088	96/506 (19%)
		TCP1_zeta	7..528	CDD:239458	96/506 (19%)
MKKS	NP_061336.1	Cpn60_TCP1	29..569	CDD:278544	96/506 (19%)
		chaperonin_like	32..476	CDD:295468	95/503 (19%)
		Substrate-binding apical domain	198..370		33/179 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900