Protein Alignment CCT6 and TCP1

DIOPT Version :9

• Sequence 1: NP_573066.1
• Gene: CCT6 / 32518
• FlyBaseID: FBgn0027329
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_110379.2
• Gene: TCP1 / 6950
• HGNCID: 11655
• Length: 556
• Species: Homo sapiens
• Alignment Length: 521
• Identity: 144/521 - (27%)
• Similarity: 276/521 - (52%)
• Gaps: 27/521 - (5%)

  Fly    23 NISAAKGLQDVMRTNLGPKGTVKMLVSGAGDIKITKDGNVLLHEMQIQHPTASMIARASTAQDDS 87
            |:.||..:.::::::|||.|..||||...||:.||.||..:|..::::||.|.::...:..||..
Human    21 NVMAAASIANIVKSSLGPVGLDKMLVDDIGDVTITNDGATILKLLEVEHPAAKVLCELADLQDKE 85

  Fly    88 TGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKALEVLDQ--VKVPVEINKKNLVE 150
            .|||||:.|::..||||.||..:.:.:||..:..|:..|..:|:..:::  :....|:.:..|:.
Human    86 VGDGTTSVVIIAAELLKNADELVKQKIHPTSVISGYRLACKEAVRYINENLIVNTDELGRDCLIN 150

  Fly   151 VANTSLKTKVHPALADLLTDVCVNAVLTIASAD-KTKP-VDLHMVELMEMQHKSDTDTQLVRGLV 213
            .|.||:.:|:.....|...::.|:|||.|...| :.:| ..::.|.:::...:|..::.|:.|..
Human   151 AAKTSMSSKIIGINGDFFANMVVDAVLAIKYTDIRGQPRYPVNSVNILKAHGRSQMESMLISGYA 215

  Fly   214 MDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFFYKTAEEREAFVRAEREFIDQRVKKVIE 278
            ::.......||||:.||.|...:.||:..|.::.........|:.:...:.|.:...:|::|::
Human   216 LNCVVGSQGMPKRIVNAKIACLDFSLQKTKMKLGVQVVITDPEKLDQIRQRESDITKERIQKIL- 279

  Fly   279 LKRSVCDGTDKTFVLINQKGIDPISLDALAKEGILALRRAKRRNMERLSLACGGTAMNSFDDLQE 343
                 ..|.:   |::...|||.:.|....:.|.:|:||..:|:::|::.|.|.|.:::..:|:.
Human   280 -----ATGAN---VILTTGGIDDMCLKYFVEAGAMAVRRVLKRDLKRIAKASGATILSTLANLEG 336

  Fly   344 EH------LGYAGVVYEHVLGENKYTFVEDCKNPLSVTILIKGPNKHTITQIKDAIRDGLRAINN 402
            |.      ||.|..|.:..:.:::...:::.|...|.:|:::|.|.....:::.::.|.|..:..
Human   337 EETFEAAMLGQAEEVVQERICDDELILIKNTKARTSASIILRGANDFMCDEMERSLHDALCVVKR 401

  Fly   403 TIADKALVPGAGAFEVRAYNELVAFKDTIKGKSRLAVQAFADALLVIPKTLAVNSGYDAQDTIVK 467
            .:..|::|||.||.|......|..:..::..:.:||:..||.:|||||.|||||:..|:.|.:.|
Human   402 VLESKSVVPGGGAVEAALSIYLENYATSMGSREQLAIAEFARSLLVIPNTLAVNAAQDSTDLVAK 466

  Fly   468 LTV---EDRLSPE-----LVGLDLATGEPMKPVDLGVYDNYIVKKQILNSCSIIASNLLLVDEVM 524
            |..   |.:::||     .:||||:.|:|......||::..|||.:.|...:..|..:|.:|:::
Human   467 LRAFHNEAQVNPERKNLKWIGLDLSNGKPRDNKQAGVFEPTIVKVKSLKFATEAAITILRIDDLI 531

  Fly   525 R 525
            :
Human   532 K 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	chap_CCT_zeta	3..532	CDD:274088	144/521 (28%)
		TCP1_zeta	7..528	CDD:239458	144/521 (28%)
TCP1	NP_110379.2	TCP1_alpha	9..535	CDD:239451	144/521 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810