Protein Alignment CCT6 and Mkks

DIOPT Version :10

• Sequence 1: NP_573066.1
• Gene: CCT6 / 32518
• FlyBaseID: FBgn0027329
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_067502.2
• Gene: Mkks / 59030
• MGIID: 1891836
• Length: 570
• Species: Mus musculus
• Alignment Length: 488
• Identity: 104/488 - (21%)
• Similarity: 177/488 - (36%)
• Gaps: 88/488 - (18%)

  Fly    24 ISAAKGLQDVMRTNLGPKGTVKMLVSGAGD-IKITKDGNVLLHEMQIQHP-----TASMIARAST 82
            :|..||   |:.:..||.|.:|.|.:|.|. :..|...:.||..:.:.||     |:|:....|.
Mouse    26 LSVLKG---VIASCYGPSGRLKQLHNGLGGCVYTTSQSSALLRNLSVTHPVLKILTSSVQNHVSC 87

  Fly    83 AQD-------------------DSTGDGTTTTVMLIGELLKQADIYL-SEGLHPRIMTDGFEKAR 127
            ..|                   |.|   ..|.:.|...||.....|| ||....||
Mouse    88 FSDCGLFTAILCCNLIENIQRLDLT---PATAIKLNKYLLSLCTSYLKSEACSCRI--------- 140

  Fly   128 DKALEVLDQVKVPVEINKKN-LVEVANTSLKTKVHPALADLLTD-----VCVNAVLTIASADKTK 186
                        ||:....: .:.:.::.|.:|....|....||     :....:|||..:.:.:
Mouse   141 ------------PVDFRSTHTFLSLVHSILTSKPACMLTRKETDHIGALILKAFLLTIPESTEER 193

  Fly   187 PVDLHMVELMEMQHKSDTDTQLVRGLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFF 251
            .| |....::.::.:..||:.::.||:::  |....:.:.|.........|:|.....   ||.|
Mouse   194 MV-LGKSIIVPLKGQRVTDSTVLPGLLIE--ASEVQLRRLLPTQKASGLRVALFCTSL---SGDF 252

  Fly   252 YKTAE---EREAFVRAEREFIDQRVKKVIELKRSVCDGTDKTFVLINQKGIDPISLDALAKEGIL 313
            ....|   .....|..|...::|    ::.|.|.:.  ||...:::.||.|.|......::..::
Mouse   253 SNAGEGVVVAHYQVSLENAVLEQ----LLNLGRRLV--TDHVDLVLCQKVIHPSLKQFFSERHVM 311

  Fly   314 ALRRAKRRNMERLSLACGGTAMNSFDDLQEEHLGYAGVVYEHVLGENKYTFVEDCKNPLSV-TIL 377
            |:.|.....||.||...|.|.:.|.:.:.....|....|.....|...  |.....|..:| |:|
Mouse   312 AIDRVGVTLMESLSKVTGATPIGSLNPIVSTTYGSVKDVCSARFGSKH--FFHLLPNEATVCTLL 374

  Fly   378 IKGPNKHTITQIKDAIRDGLRAINNTIADKALVPGAGAFE--VRAY---------NELVAFKDTI 431
            :...|.....::|...:..:..:..||.:..::.|.|..|  :.||         ..:|......
Mouse   375 LCSRNDTAWEELKLTCQTAMHVLQLTIKEPWVLLGGGCTETHLAAYVRHKVHHEAEAIVRDDGCT 439

  Fly   432 KGKSRLAVQAFADALLVIPKTLAVNSGYDAQDT 464
            :.|..:|.:||..||..:..:|..:.|....||
Mouse   440 QAKLHVAAEAFCSALESVAGSLEHDGGEILIDT 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	TCP1_zeta	7..528	CDD:239458	104/488 (21%)
Mkks	NP_067502.2	Cpn60_TCP1	29..569	CDD:395068	103/485 (21%)
		Substrate-binding apical domain. /evidence=ECO:0000250|UniProtKB:Q9NPJ1	198..370		37/184 (20%)