DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT6 and cct5

DIOPT Version :9

Sequence 1:	NP_573066.1	Gene:	CCT6 / 32518	FlyBaseID:	FBgn0027329	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_989340.1	Gene:	cct5 / 394966	XenbaseID:	XB-GENE-980275	Length:	541	Species:	Xenopus tropicalis

Alignment Length:	518	Identity:	167/518 - (32%)
Similarity:	274/518 - (52%)	Gaps:	22/518 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 ALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGDIKITKDGNVLLHEMQIQHPTASMIARASTA 83
            ||..:|.|||.:.:.:||:|||.|..||:|...|.:.:|.||..:|..|.:.|..|.::...|.:
Frog    33 ALKSHIMAAKAVANTLRTSLGPNGLDKMMVDKDGQVTVTNDGATILSMMDVDHQIAKLMVELSKS 97

  Fly    84 QDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKALEVLDQVKVPVEINKKN- 147
            |||..|||||..|:|.|.||:||:..|..|:||..:.||:|:|...|:|.||::.....::.:|
Frog    98 QDDEIGDGTTGVVVLAGALLEQAEQLLDRGIHPIRIADGYEQAARIAVEHLDKISDSFPVDPENL 162

  Fly   148 --LVEVANTSLKTKVHPALADLLTDVCVNAVLTIASADKTKPVDLHMVELMEMQHKSDTDTQLVR 210
              |:..|.|:|.:||.......:.::.||::||:|..|: |.||..::::.........||||::
Frog   163 EPLIRTAMTTLGSKVINRCHRQMAEIAVNSILTVADMDR-KDVDFELIKVEGKVGGKLEDTQLIK 226

  Fly   211 GLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFFYKTAEEREAFVRAEREFIDQRVKK 275
            |:::|....||.|||.:::|.|.......|..|.:........:.|:.:|..:.|:|       |
Frog   227 GVIVDKDFSHPQMPKVVKDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKE-------K 284

  Fly   276 VIELKRSVCD-GTDKTFVLINQKGIDPISLDALAKEGILALRRAKRRNMERLSLACGGTAMNSFD 339
            .:|:.:.:.| |.:   :.|.|.|.|..:...|.:..:.|:|......:|.:::|.||..:..|.
Frog   285 FLEMVKQIKDTGAN---LAICQWGFDDEANHLLLQNELPAVRWVGGPEIELIAIATGGRIVPRFC 346

  Fly   340 DLQEEHLGYAGVVYEHVLG--ENKYTFVEDCKNPLSVTILIKGPNKHTITQIKDAIRDGLRAINN 402
            :|..|.|||||:|.|...|  :::...:|.|||..:|||.|:|.||..|.:.|.::.|.|..|.|
Frog   347 ELTPEKLGYAGIVKEISFGTTKDRMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRN 411

  Fly   403 TIADKALVPGAGAFEVRAYNELVAFKDTIKGKSRLAVQAFADALLVIPKTLAVNSGYDAQDTIVK 467
            .:.|..:|.|.||.|:.....:....|......:.|::||||||.:||.:||.|||.:...|:.:
Frog   412 LVRDNRIVYGGGAAEISCALAVSEAADKCPSLEQYAMRAFADALEIIPMSLAENSGMNPIQTMTE 476

  Fly   468 L-TVEDRLSPELVGLD-LATG-EPMKPVDLGVYDNYIVKKQILNSCSIIASNLLLVDEVMRAG 527
            : :.:.:.|...:|:| |..| ..||  ...|.:..|.|||.::..:.:...:|.:|::.|.|
Frog   477 VRSKQVKESNPALGIDCLHKGTNDMK--QQHVIETLIGKKQQISLATQVVKMILKIDDIRRPG 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	chap_CCT_zeta	3..532	CDD:274088	167/518 (32%)
CCT6	NP_573066.1	TCP1_zeta	7..528	CDD:239458	167/518 (32%)
cct5	NP_989340.1	TCP1_epsilon	10..535	CDD:239455	165/514 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920