DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCT6 and cct3

DIOPT Version :9

Sequence 1:	NP_573066.1	Gene:	CCT6 / 32518	FlyBaseID:	FBgn0027329	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_989339.1	Gene:	cct3 / 394965	XenbaseID:	XB-GENE-6250478	Length:	548	Species:	Xenopus tropicalis

Alignment Length:	522	Identity:	157/522 - (30%)
Similarity:	280/522 - (53%)	Gaps:	16/522 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 NPKAEFARAAQALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGDIKITKDGNVLLHEMQIQHP 72
            |.|.|..|..|  :.||:|||.:.|::||.|||:..:|||:...|.|.:|.|||.:|.|:|:|||
Frog    12 NIKRESGRKVQ--SGNINAAKTIADIIRTCLGPRAMMKMLLDPMGGIVMTNDGNAILREIQVQHP 74

  Fly    73 TASMIARASTAQDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKALEVLDQV 137
            .|..:...|..||:..|||||:.::|.||:|..|:.:|.:.:||.::...:.||.|..:..|.::
Frog    75 AAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEQFLEQQMHPTVVISAYRKALDDMVSTLKEI 139

  Fly   138 KVPVEINKKNL-VEVANTSLKTKVHPALADLLTDVCVNAVLTIASADK-TKPVDLHMVELME-MQ 199
            ..||:.|.:.| :::.|:::.||.....||:...:.::||.|:...:. .|.:|:.....:| :.
Frog   140 STPVDTNDRELMLKIINSAVNTKAIKRWADMACGIALDAVKTVELEENGRKEIDIKKYAKVEKIP 204

  Fly   200 HKSDTDTQLVRGLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFFYKTAEEREAFVRA 264
            .....|:.::||::::....||.|.:.::|..|:..:.||||:|.|..:.......|:....::.
Frog   205 GGIIEDSCVLRGVMVNKDVTHPKMRRLIKNPRIVLLDCSLEYKKGESQTEIEITREEDFARILQM 269

  Fly   265 EREFIDQRVKKVIELKRSVCDGTDKTFVLINQKGIDPISLDALAKEGILALRRAKRRNMERLSLA 329
            |.|:|.|..:.:|.||..         |:|.:|||..::...|.|..|.|:||.::.:..|::.|
Frog   270 EEEYIQQVCEDIIRLKPD---------VVITEKGISDLAQHYLVKANITAIRRVRKTDNNRIARA 325

  Fly   330 CGGTAMNSFDDLQEEHLGYAGVVYE-HVLGENKYTFVEDCKNPLSVTILIKGPNKHTITQIKDAI 393
            ||....:..|:|:||.:|....::| ..:|:..:||:.:||:|.:.||:::|.:|..:.:::..:
Frog   326 CGARIGSRTDELREEDVGTGAGLFEIKKIGDEYFTFITECKDPKACTIVLRGASKEILAEVERNL 390

  Fly   394 RDGLRAINNTIADKALVPGAGAFEVRAYNELVAFKDTIKGKSRLAVQAFADALLVIPKTLAVNSG 458
            :|.::...|.:.|..||||.||.|:...:.|.....|:.|..:...:|.|.||.|||:||..|.|
Frog   391 QDAMQVCRNVVIDPHLVPGGGAAEMSVAHILTEKSKTMTGVEQWPYRAVAQALEVIPRTLVQNCG 455

  Fly   459 YDAQDTIVKLTVE-DRLSPELVGLDLATGEPMKPVDLGVYDNYIVKKQILNSCSIIASNLLLVDE 522
            ......:..|..: .:...:..|:|...|..:...:||:::...||.|...:....|..||.:|:
Frog   456 ASTIRVLTSLRAKHTQEGCQTWGVDGEAGVLVDMKELGIWEPLAVKLQTYKTAVETAILLLRIDD 520

  Fly   523 VM 524
            ::
Frog   521 IV 522

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	chap_CCT_zeta	3..532	CDD:274088	157/522 (30%)
CCT6	NP_573066.1	TCP1_zeta	7..528	CDD:239458	157/522 (30%)
cct3	NP_989339.1	chap_CCT_gamma	5..528	CDD:274085	157/522 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010