Protein Alignment CCT6 and HSPD1

DIOPT Version :9

• Sequence 1: NP_573066.1
• Gene: CCT6 / 32518
• FlyBaseID: FBgn0027329
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_002147.2
• Gene: HSPD1 / 3329
• HGNCID: 5261
• Length: 573
• Species: Homo sapiens
• Alignment Length: 573
• Identity: 113/573 - (19%)
• Similarity: 223/573 - (38%)
• Gaps: 126/573 - (21%)

  Fly    17 AQALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGDIKITKDGNVLLHEMQI----QHPTASMI 77
            |.|.|:.:.....|.|.:...:||||...::....|..|:||||..:...:.:    ::..|.::
Human    34 ADARALMLQGVDLLADAVAVTMGPKGRTVIIEQSWGSPKVTKDGVTVAKSIDLKDKYKNIGAKLV 98

  Fly    78 ARASTAQDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKALEVLDQVKVPVE 142
            ...:...::..||||||..:|...:.|:....:|:|.:|..:..|...|.|..:..|.:...||
Human    99 QDVANNTNEEAGDGTTTATVLARSIAKEGFEKISKGANPVEIRRGVMLAVDAVIAELKKQSKPV- 162

  Fly   143 INKKNLVEVANTSLK--TKVHPALADLLTDVCVNAVLTIASADKTKPVDLHMVELMEMQHKSDTD 205
            ...:.:.:||..|..  .::...::|.:..|....|:|:... ||...:|.::|
Human   163 TTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKDG-KTLNDELEIIE----------- 215

  Fly   206 TQLVRGLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFFYKTAEEREAFVRAEREFID 270
                 |:..|.|             ||               |.:|..|::.::.      ||.|
Human   216 -----GMKFDRG-------------YI---------------SPYFINTSKGQKC------EFQD 241

  Fly   271 QRV----KKVIELKR-----SVCDGTDKTFVLINQKGIDPISLDALA----KEG--ILALRRA-- 318
            ..|    ||:..::.     .:.:...|..|:| .:.:|..:|..|.    |.|  ::|::..
Human   242 AYVLLSEKKISSIQSIVPALEIANAHRKPLVII-AEDVDGEALSTLVLNRLKVGLQVVAVKAPGF 305

  Fly   319 ---KRRNMERLSLACGGTAMN------SFDDLQEEHLGYAGVV---------------------- 352
               ::..::.:::|.||....      :.:|:|...||..|.|
Human   306 GDNRKNQLKDMAIATGGAVFGEEGLTLNLEDVQPHDLGKVGEVIVTKDDAMLLKGKGDKAQIEKR 370

  Fly   353 YEHVLGENKYTFVEDCKNPLS---------VTIL-IKGPNKHTITQIKDAIRDGLRAINNTIADK 407
            .:.::.:...|..|..|..|:         |.:| :.|.:...:.:.||.:.|.|.|....: ::
Human   371 IQEIIEQLDVTTSEYEKEKLNERLAKLSDGVAVLKVGGTSDVEVNEKKDRVTDALNATRAAV-EE 434

  Fly   408 ALVPGAGAFEVRAYNELVAFKDTIKGKSRLAVQAFADALLVIPKTLAVNSGYDAQDTIVKLTVED 472
            .:|.|.|...:|....|.:.....:.: ::.::.....|.:...|:|.|:|.:....:.|:
Human   435 GIVLGGGCALLRCIPALDSLTPANEDQ-KIGIEIIKRTLKIPAMTIAKNAGVEGSLIVEKI---- 494

  Fly   473 RLSPELVGLDLATGEPMKPVDLGVYD-NYIVKKQILNSCSIIASNLLLVDEVM 524
            ..|...||.|...|:.:..|:.|:.| ..:|:..:|::..:  ::||...||:
Human   495 MQSSSEVGYDAMAGDFVNMVEKGIIDPTKVVRTALLDAAGV--ASLLTTAEVV 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	chap_CCT_zeta	3..532	CDD:274088	113/573 (20%)
		TCP1_zeta	7..528	CDD:239458	113/573 (20%)
HSPD1	NP_002147.2	GroEL	28..548	CDD:239460	113/573 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900