DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CCT6 and cct6

DIOPT Version :9

Sequence 1:	NP_573066.1	Gene:	CCT6 / 32518	FlyBaseID:	FBgn0027329	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_595369.1	Gene:	cct6 / 2541128	PomBaseID:	SPBC646.11	Length:	535	Species:	Schizosaccharomyces pombe

Alignment Length:	534	Identity:	323/534 - (60%)
Similarity:	412/534 - (77%)	Gaps:	10/534 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ISLLNPKAEFARAAQALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGDIKITKDGNVLLHEMQ 68
            :||||||||..:.||||.:|||||.|||||:::||||.||.||||.|||.||:||||.|||.|||
pombe     2 LSLLNPKAESIQRAQALQVNISAAIGLQDVLKSNLGPTGTTKMLVDGAGAIKLTKDGKVLLTEMQ 66

  Fly    69 IQHPTASMIARASTAQDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKALEV 133
            ||:||||.||:|:|||||:||||||:..:|:|||||||::|:.|||||.:::|||..|:::||..
pombe    67 IQNPTASCIAKAATAQDDATGDGTTSVCLLVGELLKQAELYIREGLHPSLISDGFNLAKNEALTF 131

  Fly   134 LDQVKVPVEINKKNLVEVANTSLKTKVHPALADLLTDVCVNAVLTIASADKTKPVDLHMVELMEM 198
            ||..|...|::::.|:.||.|||.||:...:.:.|....|:|:|||...|  :|:||||||:|:|
pombe   132 LDSFKTDFEVDREVLLNVAKTSLSTKISSKVVESLAPAVVDAILTIRRPD--EPIDLHMVEIMKM 194

  Fly   199 QHKSDTDTQLVRGLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFFYKTAEEREAFVR 263
            |::|.:||||:|||::|||||||||||:::|||||..||||||||:|:||||||.|:|:||..|.
pombe   195 QNRSASDTQLIRGLLLDHGARHPDMPKQVKNAYILILNVSLEYEKSEINSGFFYSTSEQRERLVE 259

  Fly   264 AEREFIDQRVKKVIELKRSVCDGTDKT--FVLINQKGIDPISLDALAKEGILALRRAKRRNMERL 326
            :||:|:|.:::|::|||:.||: .|.|  ||:||||||||:|||.|||.||:|||||||||||||
pombe   260 SERKFVDNKLRKIVELKKEVCE-RDPTANFVIINQKGIDPLSLDVLAKNGIMALRRAKRRNMERL 323

  Fly   327 SLACGGTAMNSFDDLQEEHLGYAGVVYEHVLGENKYTFVEDCKNPLSVTILIKGPNKHTITQIKD 391
            .|||||.|.||.|||..|.||:||.|||..|||.|||||||.|:|.|.||||.|||.:||.||:|
pombe   324 QLACGGVAQNSVDDLNPEVLGWAGSVYERTLGEEKYTFVEDVKDPKSATILIHGPNTYTIQQIQD 388

  Fly   392 AIRDGLRAINNTIADKALVPGAGAFEVRAYNEL---VAFKDTIKGKSRLAVQAFADALLVIPKTL 453
            |.||||||:.|.:.|..|:.|||||||.....|   .|.|: :|||:::.|.|:|||||:|||||
pombe   389 ATRDGLRAVKNAVEDNCLIVGAGAFEVACAAHLRNKFAAKE-VKGKAKMGVYAYADALLIIPKTL 452

  Fly   454 AVNSGYDAQDTIVKLTVEDRLSPELVGLDLATGEPMKPVDLGVYDNYIVKKQILNSCSIIASNLL 518
            |.||.||.||.||.|. |:......|||||.||.|..|...|:||||.|.:.:|:|.::|||||:
pombe   453 AANSSYDTQDAIVALQ-EEASEGYKVGLDLKTGMPFDPEVEGIYDNYRVIRHMLHSATVIASNLI 516

  Fly   519 LVDEVMRAGMTSLK 532
            .||:::|||.:|||
pombe   517 SVDQILRAGRSSLK 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	chap_CCT_zeta	3..532	CDD:274088	321/532 (60%)
CCT6	NP_573066.1	TCP1_zeta	7..528	CDD:239458	317/525 (60%)
cct6	NP_595369.1	chap_CCT_zeta	2..530	CDD:274088	321/532 (60%)
cct6	NP_595369.1	TCP1_zeta	5..526	CDD:239458	317/525 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	581	1.000	Domainoid score	I31
eggNOG	1	0.900	-	-		E1_COG0459
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1336
Inparanoid	1	1.050	626	1.000	Inparanoid score	I144
OMA	1	1.010	-	-		QHG54122
OrthoFinder	1	1.000	-	-		FOG0003188
OrthoInspector	1	1.000	-	-		oto100647
orthoMCL	1	0.900	-	-		OOG6_101716
Panther	1	1.100	-	-	LDO	PTHR11353
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1491
SonicParanoid	1	1.000	-	-		X2146
TreeFam	1	0.960	-	-
	14	13.860