DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CCT6 and cct-5

DIOPT Version :9

Sequence 1:	NP_573066.1	Gene:	CCT6 / 32518	FlyBaseID:	FBgn0027329	Length:	533	Species:	Drosophila melanogaster
Sequence 2:	NP_741117.1	Gene:	cct-5 / 175588	WormBaseID:	WBGene00000380	Length:	542	Species:	Caenorhabditis elegans

Alignment Length:	513	Identity:	168/513 - (32%)
Similarity:	267/513 - (52%)	Gaps:	20/513 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGDIKITKDGNVLLHEMQIQHPTASMIARAST 82
            :|:..:|.||:.:.:.:||:|||:|..|||||..||:.||.||..::.:|.:||..|.::...|.
Worm    33 EAVKSHILAARAVANTLRTSLGPRGLDKMLVSPDGDVTITNDGATIMEKMDVQHHVAKLMVELSK 97

  Fly    83 AQDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKALEVLDQV--KVPVEINK 145
            :||...|||||..|:|.|.||::|:..:..|:||..:.|||:.|..||||.||.:  |.||| |:
Worm    98 SQDHEIGDGTTGVVVLAGALLEEAEKLIDRGIHPIKIADGFDLACKKALETLDSISDKFPVE-NR 161

  Fly   146 KNLVEVANTSLKTKVHPALADLLTDVCVNAVLTIASADKTKPVDLHMVELMEMQHKSDTDTQLVR 210
            :.|||.|.|||.:|:.........::.|:|||::|..: :|.|:..|:::.........||.||:
Worm   162 ERLVETAQTSLGSKIVNRSLRQFAEIAVDAVLSVADIE-SKDVNFEMIKMEGKVGGRLEDTILVK 225

  Fly   211 GLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFFYKTAEEREAFVRAEREFIDQRVKK 275
            |:|:|....||.|||.|:||.:.......|..|.:........:.|:.:|....|||..:..:::
Worm   226 GIVIDKTMSHPQMPKELKNAKVAILTCPFEPPKPKTKHKLDITSTEDFKALRDYERETFETMIRQ 290

  Fly   276 VIELKRSVCDGTDKTFVLINQKGIDPISLDALAKEGILALRRAKRRNMERLSLACGGTAMNSFDD 340
            |.|...::.         |.|.|.|..:...|....:.|:|......:|.|::|.....:..|.:
Worm   291 VKESGATLA---------ICQWGFDDEANHLLQANDLPAVRWVGGPEIELLAIATNARIVPRFSE 346

  Fly   341 LQEEHLGYAGVVYEHVLG--ENKYTFVEDCKNPLSVTILIKGPNKHTITQIKDAIRDGLRAINNT 403
            |.:|.||.||:|.|...|  :::...:|.|.|..:|||.::|.||..|.:.|.|:.|.|..|.|.
Worm   347 LSKEKLGTAGLVREITFGAAKDRMLSIEQCPNNKAVTIFVRGGNKMIIDEAKRALHDALCVIRNL 411

  Fly   404 IADKALVPGAGAFEVRAYNELVAFKDTIKGKSRLAVQAFADALLVIPKTLAVNSGYDAQDTIVKL 468
            :.|..:|.|.|:.|:.|..::....|.|.|..:.|.:||||||..||..||.|||....|.:..|
Worm   412 VRDSRIVYGGGSAELAAAIQVAKEADRIDGIEQYAFRAFADALESIPMALAENSGLAPIDALSDL 476

  Fly   469 TVED-RLSPELVGLD--LATGEPMKPVDLGVYDNYIVKKQILNSCSIIASNLLLVDEV 523
            ..:. ......:|:|  .|....||  :..|.:..:.|::.::..:.:...:|.:|:|
Worm   477 KAKQIETGKSSLGIDAVFAGTNDMK--EQKVIETLLSKREQISLATQVVRMILKIDDV 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	chap_CCT_zeta	3..532	CDD:274088	168/513 (33%)
CCT6	NP_573066.1	TCP1_zeta	7..528	CDD:239458	168/513 (33%)
cct-5	NP_741117.1	TCP1_epsilon	11..534	CDD:239455	168/513 (33%)
cct-5	NP_741117.1	Cpn60_TCP1	45..532	CDD:278544	163/499 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D207515at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920