Protein Alignment CCT6 and Cct2

DIOPT Version :10

• Sequence 1: NP_573066.1
• Gene: CCT6 / 32518
• FlyBaseID: FBgn0027329
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_031662.2
• Gene: Cct2 / 12461
• MGIID: 107186
• Length: 535
• Species: Mus musculus
• Alignment Length: 544
• Identity: 145/544 - (26%)
• Similarity: 270/544 - (49%)
• Gaps: 44/544 - (8%)

  Fly     1 MASISLLNPKAEFARAAQALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGD--IKITKDGNVL 63
            :|.:::....|:..||..|...:...|..:.|::::.|||||..|:|:|...|  :.:|.||..:
Mouse     6 LAPVNIFKAGADEERAETARLSSFIGAIAIGDLVKSTLGPKGMDKILLSSGRDAALMVTNDGATI 70

  Fly    64 LHEMQIQHPTASMIARASTAQDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARD 128
            |..:.:.:|.|.::...|..|||..|||||:..:|..|||::|:..:::.:||:.:..|:.:|..
Mouse    71 LKNIGVDNPAAKVLVDMSRVQDDEVGDGTTSVTVLAAELLREAESLIAKKIHPQTIISGWREATK 135

  Fly   129 KALEVL---------DQVKVPVEINKKNLVEVANTSLKTKVHPALADLLTDVCVNAVLTIASADK 184
            .|.|.|         |:.:.     .::|:.:|.|:|.:|:.....|..|.:.|.|||.:..:.
Mouse   136 AAREALLSSAVDHGSDEARF-----WQDLMNIAGTTLSSKLLTHHKDHFTKLAVEAVLRLKGSG- 194

  Fly   185 TKPVDLHMVELMEMQHKSDTDTQLVRGLVMDH--GARHPDMPKRLENAYILTANVSLEYEKAEVN 247
                :|..:.:::....|..|:.|..|.::|.  |.   :.|||:|||.||.||..::.:|.::
Mouse   195 ----NLEAIHVIKKLGGSLADSYLDEGFLLDKKIGV---NQPKRIENAKILIANTGMDTDKIKI- 251

  Fly   248 SGFFYKTAEEREAFV----RAEREFIDQRVKKVIELKRSV-CDGTDKTFVLINQKGIDPISLDAL 307
              |..:...:..|.|    .||:|.:.::|:::  ||..: |        .||::.|........
Mouse   252 --FGSRVRVDSTAKVAEIEHAEKEKMKEKVERI--LKHGINC--------FINRQLIYNYPEQLF 304

  Fly   308 AKEGILALRRAKRRNMERLSLACGGTAMNSFDDLQEEHLGYAGVVYEHVLGENKYTFVEDCKNPL 372
            ...|::|:..|....:|||:|..||...::||..:...||...::.|.::||:|...........
Mouse   305 GAAGVMAIEHADFAGVERLALVTGGEIASTFDHPELVKLGSCKLIEEVMIGEDKLIHFSGVALGE 369

  Fly   373 SVTILIKGPNKHTITQIKDAIRDGLRAINNTIADKALVPGAGAFEVRAYNELVAFKDTIKGKSRL 437
            :.||:::|..:..:.:.:.::.|.|..:..|:.|...|.|.|..|:...:.:....:...||..:
Mouse   370 ACTIVLRGATQQILDEAERSLHDALCVLAQTVKDPRTVYGGGCSEMLMAHAVTQLANRTPGKEAV 434

  Fly   438 AVQAFADALLVIPKTLAVNSGYDAQDTIVKLTVEDRLSPELVGLDLATGEPMKPVDLGVYDNYIV 502
            |:::||.||.::|..:|.|:|||:.|.:.:|...........|||:..|.......||:.:::.|
Mouse   435 AMESFAKALRMLPTIIADNAGYDSADLVAQLRAAHSEGHITAGLDMKEGTIGDMAVLGITESFQV 499

  Fly   503 KKQILNSCSIIASNLLLVDEVMRA 526
            |:|:|.|.:..|..:|.||.:::|
Mouse   500 KRQVLLSAAEAAEVILRVDNIIKA 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	TCP1_zeta	7..528	CDD:239458	144/538 (27%)
Cct2	NP_031662.2	TCP1_beta	11..527	CDD:239452	144/539 (27%)