Protein Alignment CCT6 and CCT6B

DIOPT Version :10

• Sequence 1: NP_573066.1
• Gene: CCT6 / 32518
• FlyBaseID: FBgn0027329
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_006575.2
• Gene: CCT6B / 10693
• HGNCID: 1621
• Length: 530
• Species: Homo sapiens
• Alignment Length: 532
• Identity: 362/532 - (68%)
• Similarity: 449/532 - (84%)
• Gaps: 2/532 - (0%)

  Fly     1 MASISLLNPKAEFARAAQALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGDIKITKDGNVLLH 65
            ||:|..:|.|||.|||..|||:||.||:|||||:|||||||||:|||||||||||:||||||||.
Human     1 MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDGNVLLD 65

  Fly    66 EMQIQHPTASMIARASTAQDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKA 130
            ||||||||||:||:.:|||||.||||||:.|::|||||||||:|:||||||||:.:|||.|:.||
Human    66 EMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIAEGFEAAKIKA 130

  Fly   131 LEVLDQVKVPVEINKKNLVEVANTSLKTKVHPALADLLTDVCVNAVLTIASADKTKPVDLHMVEL 195
            ||||::|||..|:.:|.|::||.|||:||||..|||:||:|.|::||.:....  .|:||.|||:
Human   131 LEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVRRPG--YPIDLFMVEI 193

  Fly   196 MEMQHKSDTDTQLVRGLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFFYKTAEEREA 260
            |||:||..|||:|::|||:|||||||||.||:|:|:||..||||||||.|||||||||||||:|.
Human   194 MEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEK 258

  Fly   261 FVRAEREFIDQRVKKVIELKRSVCDGTDKTFVLINQKGIDPISLDALAKEGILALRRAKRRNMER 325
            .|:|||:||:.||:|:|:||..||..::|.||:||||||||.|||:|||.||:||||||||||||
Human   259 LVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMER 323

  Fly   326 LSLACGGTAMNSFDDLQEEHLGYAGVVYEHVLGENKYTFVEDCKNPLSVTILIKGPNKHTITQIK 390
            |||||||.|:|||:||..:.||:||:|||:.|||.|:||:|:|.||.|||:|:|||||||:||:|
Human   324 LSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVK 388

  Fly   391 DAIRDGLRAINNTIADKALVPGAGAFEVRAYNELVAFKDTIKGKSRLAVQAFADALLVIPKTLAV 455
            ||||||||||.|.|.|..:||||||.||.....||.:|::|||::||.|||||||||:|||.||.
Human   389 DAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQ 453

  Fly   456 NSGYDAQDTIVKLTVEDRLSPELVGLDLATGEPMKPVDLGVYDNYIVKKQILNSCSIIASNLLLV 520
            |:|||.|:|:||:..|...|.:|||:||.|||||...|.||:|||.||||:|:||::||:|:|||
Human   454 NAGYDPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLV 518

  Fly   521 DEVMRAGMTSLK 532
            ||:|||||:|||
Human   519 DEIMRAGMSSLK 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	TCP1_zeta	7..528	CDD:239458	354/520 (68%)
CCT6B	NP_006575.2	chap_CCT_zeta	3..530	CDD:274088	358/528 (68%)