Protein Alignment CCT6 and CCT4

DIOPT Version :10

• Sequence 1: NP_573066.1
• Gene: CCT6 / 32518
• FlyBaseID: FBgn0027329
• Length: 533
• Species: Drosophila melanogaster
• Sequence 2: NP_006421.2
• Gene: CCT4 / 10575
• HGNCID: 1617
• Length: 539
• Species: Homo sapiens
• Alignment Length: 520
• Identity: 161/520 - (30%)
• Similarity: 269/520 - (51%)
• Gaps: 28/520 - (5%)

  Fly    15 RAAQALAINISAAKGLQDVMRTNLGPKGTVKMLVSGAGDIKITKDGNVLLHEMQIQHPTASMIAR 79
            :.||....||||||.:.|.:||:|||||..||:..|.||:.||.||..:|.:||:.||.|.|:..
Human    29 KPAQIRFSNISAAKAVADAIRTSLGPKGMDKMIQDGKGDVTITNDGATILKQMQVLHPAARMLVE 93

  Fly    80 ASTAQDDSTGDGTTTTVMLIGELLKQADIYLSEGLHPRIMTDGFEKARDKALEVLDQVKVPVEI- 143
            .|.|||...|||||:.|::.|.||......|.:|:||.|:::.|:||.:|.:|:|..:..|||:
Human    94 LSKAQDIEAGDGTTSVVIIAGSLLDSCTKLLQKGIHPTIISESFQKALEKGIEILTDMSRPVELS 158

  Fly   144 NKKNLVEVANTSLKTKVHPALADLLTDVCVNAVLTIASADKTKPVDLHMVELMEMQHKSDTDTQL 208
            :::.|:..|.|||.:||....:.||:.:.||||:.:........|||..:::::....:..|.:|
Human   159 DRETLLNSATTSLNSKVVSQYSSLLSPMSVNAVMKVIDPATATSVDLRDIKIVKKLGGTIDDCEL 223

  Fly   209 VRGLVMDHGARHPDMPKRLENAYILTANVSLEYEKAEVNSGFFYKTAEEREAFVRAEREFIDQRV 273
            |.|||:.....:..: .|:|.|.|......|...|.::::........:.:..:|.||.:|...|
Human   224 VEGLVLTQKVSNSGI-TRVEKAKIGLIQFCLSAPKTDMDNQIVVSDYAQMDRVLREERAYILNLV 287

  Fly   274 KKVIELKRSVCDGTDKTFVLINQKGI-----DPISLDALAKEGILALRRAKRRNMERLSLACGGT 333
            |   ::|::.|:      ||:.||.|     ..::|..|.|..|:.::..:|.::|.:....|..
Human   288 K---QIKKTGCN------VLLIQKSILRDALSDLALHFLNKMKIMVIKDIEREDIEFICKTIGTK 343

  Fly   334 AMNSFDDLQEEHLGYAGVVYE-HVLGENKYTFVEDCKNP-LSVTILIKGPNKHTITQIKDAIRDG 396
            .:...|....:.||.|.:..| ::.|..|...:..|.:| .:|||:::|.||..|.:.:.:|.|.
Human   344 PVAHIDQFTADMLGSAELAEEVNLNGSGKLLKITGCASPGKTVTIVVRGSNKLVIEEAERSIHDA 408

  Fly   397 LRAINNTIADKALVPGAGAFEVRAYNELVAFKDTIKGKSRLAVQAFADALLVIPKTLAVNSGYDA 461
            |..|...:..:||:.|.||.|:.....|..:..|:.|.....|:|||||:.|||.|||.|:|.:.
Human   409 LCVIRCLVKKRALIAGGGAPEIELALRLTEYSRTLSGMESYCVRAFADAMEVIPSTLAENAGLNP 473

  Fly   462 QDTIVKLTVEDRLSPELVGLDLATGEPMKPVDLGVYDNYIVKKQILNSCSIIASNLLLVDEVMRA 526
            ..|:.:|........:..|:::..|        |:  :.|:::.::....:..|.|.|..|.:|:
Human   474 ISTVTELRNRHAQGEKTAGINVRKG--------GI--SNILEELVVQPLLVSVSALTLATETVRS 528

  Fly   527  526
            Human   529  528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CCT6	NP_573066.1	TCP1_zeta	7..528	CDD:239458	161/520 (31%)
CCT4	NP_006421.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29		161/520 (31%)
		TCP1_delta	25..538	CDD:239454	161/520 (31%)