Protein Alignment CG8944 and ZNF212

DIOPT Version :10

• Sequence 1: NP_573065.1
• Gene: CG8944 / 32517
• FlyBaseID: FBgn0030680
• Length: 762
• Species: Drosophila melanogaster
• Sequence 2: NP_036388.2
• Gene: ZNF212 / 7988
• HGNCID: 13004
• Length: 495
• Species: Homo sapiens
• Alignment Length: 249
• Identity: 63/249 - (25%)
• Similarity: 88/249 - (35%)
• Gaps: 74/249 - (29%)

  Fly   521 NHKQLHL----GGVTEIK------FNCELCTASFREKANYDEHLRRHNEELFLPSLALNHSIMEG 575
            :|:|:.|    |...::|      :.|..|..:||.|.....|||.|:
Human   292 SHRQVQLDQECGQGLKLKKDTSRPYECSECEITFRYKQQLATHLRSHS----------------- 339

  Fly   576 GLGD--DEIGVEGEESRGSGSRRKRRHAAKATDDMVDDDDRIGGGGGGGSGGGGTDIAKPYGCDV 638
            |.|.  .|   |.|||.....|.|.:                            |..||.:.|||
Human   340 GWGSCTPE---EPEESLRPRPRLKPQ----------------------------TKKAKLHQCDV 373

  Fly   639 CRRSFATPGHLNAHRIVHQDERERCYKCDYPQCNKSFVAR---NSLFE---HLKQHYSNEEFKCD 697
            |.|||:....|..|        :||:..:.|...:....|   |||..   |:....|.....|.
Human   374 CLRSFSCKVSLVTH--------QRCHLQEGPSAGQHVQERFSPNSLVALPGHIPWRKSRSSLICG 430

  Fly   698 ICGKTFKSTKNLQNHKQIHDKIKRYVCQICGSAFAQAAGLYLHKRRHNRPNGAV 751
            .|||:|....:|..|::||...:.|.|..|..:|.|...|..|::.|.|..|.:
Human   431 YCGKSFSHPSDLVRHQRIHTGERPYSCTECEKSFVQKQHLLQHQKIHQRERGGL 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8944	NP_573065.1	MADF_DNA_bdg	259..344	CDD:463144
		MADF	379..472	CDD:214738
		C2H2 Zn finger	476..496	CDD:275368
		C2H2 Zn finger	506..526	CDD:275368	2/4 (50%)
		C2H2 Zn finger	537..557	CDD:275368	8/19 (42%)
		C2H2 Zn finger	636..656	CDD:275368	9/19 (47%)
		COG5048	<666..734	CDD:227381	20/73 (27%)
		C2H2 Zn finger	666..688	CDD:275368	6/27 (22%)
		C2H2 Zn finger	696..716	CDD:275368	7/19 (37%)
		C2H2 Zn finger	724..744	CDD:275368	6/19 (32%)
ZNF212	NP_036388.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		KRAB_A-box	142..180	CDD:143639
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..290
		zf-C2H2	316..338	CDD:395048	8/21 (38%)
		C2H2 Zn finger	318..338	CDD:275370	8/19 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	337..361		9/43 (21%)
		C2H2 Zn finger	371..391	CDD:275368	10/27 (37%)
		C2H2 Zn finger	429..449	CDD:275368	7/19 (37%)
		zf-C2H2	429..449	CDD:395048	7/19 (37%)
		zf-C2H2	455..477	CDD:395048	7/21 (33%)
		C2H2 Zn finger	457..477	CDD:275368	6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..495		3/9 (33%)