DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8944 and Zfp652

DIOPT Version :9

Sequence 1:NP_573065.1 Gene:CG8944 / 32517 FlyBaseID:FBgn0030680 Length:762 Species:Drosophila melanogaster
Sequence 2:NP_001073676.1 Gene:Zfp652 / 497984 RGDID:1566329 Length:608 Species:Rattus norvegicus


Alignment Length:504 Identity:109/504 - (21%)
Similarity:174/504 - (34%) Gaps:141/504 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   317 VYKREC---------NRMA---LEKTNISTLWYFKELHFLNEVYSYNDKMSDA----VVKETSYR 365
            |||||.         ::|:   |.:|....  ||:|...:::|::..:...::    ..:|.||:
  Rat    50 VYKRESGSPYSVLADSKMSKPHLHETEEQP--YFREPRAVSDVHTVKEDRENSDDTEEEEEVSYK 112

  Fly   366 RR---------------------FSAIWNDTSTAKLLSMVKRYQCFYNRFD--PDYRSKERRGEG 407
            |.                     .|:...:|...|..|..:..:...:..|  .||      ||.
  Rat   113 REQIIVEVNLNNQTLNVSKGEKGVSSQSKETPVLKTSSEEEEEETEEDATDNSSDY------GEN 171

  Fly   408 LHQMAIELQQLIDVTTIQISKRISQL-------------RFDYSKQKMERLNSERLGKKFIANYL 459
            ..|...|.|    |..:::::|.::.             |....::|...|...   ||..|...
  Rat   172 GRQKKKEKQ----VEKVRVTQRRTRRAASVAAATTSPTPRTTRGRRKSAELPKR---KKRAAKEP 229

  Fly   460 YYDQMHFMDDDIPPFKCAHCPEIVQTLRELDLHM-LTHQPSLGGGYYCNICSIQFHNAQEFDNHK 523
            .........|:.....|..||.:..|...|:.|| :||:..    ..|:.|..:|....|...|:
  Rat   230 KAPVQKAKCDEKETLTCEKCPRVFNTRWYLEKHMNVTHRRM----QICDKCGKKFVLESELSLHQ 290

  Fly   524 QLHLGGVTEIKFNCELCTASFREKANYDEHLRRHNEELFLPSLALNHSIMEGGLGDDEIGVEGEE 588
            |..    .|....|..|..||::..:..||::            :.|     |..:.:...|..|
  Rat   291 QTD----CEKNIQCVSCNKSFKKLWSLHEHIK------------IVH-----GYAEKKFACEICE 334

  Fly   589 SRGSGSRRKRRHAAKATDDMVDDDDRIGGGGGGGSGGGGTDIAKPYGCDVCRRSFATPGHLNAHR 653
            .:.......|:|....|.||                        |:.|:.|.:||.....|..|.
  Rat   335 KKFYTMAHVRKHMVAHTKDM------------------------PFTCETCGKSFKRSMSLKVHS 375

  Fly   654 IVHQDERE-RCYKCD------------------YPQ-----CNKSFVARNSLFEHLKQHYSNEEF 694
            :.|..|:. ||..||                  :.|     |.|.|..:....||:|.|...:.|
  Rat   376 LQHSGEKPFRCENCDERFQYKYQLRSHMSIHIGHKQFMCQWCGKDFNMKQYFDEHMKTHTGEKPF 440

  Fly   695 KCDICGKTFKSTKNLQNHKQIHDKIKRYVCQICGSAFAQAAGLYLHKRR 743
            .|:||||:|.|..|::.|::.|...|.|.|.:||..|..:..|..||.:
  Rat   441 ICEICGKSFTSRPNMKRHRRTHTGEKPYPCDVCGQRFRFSNMLKAHKEK 489

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8944NP_573065.1 MADF_DNA_bdg 259..344 CDD:287510 11/38 (29%)
MADF 379..472 CDD:214738 19/107 (18%)
C2H2 Zn finger 476..496 CDD:275368 7/20 (35%)
C2H2 Zn finger 506..526 CDD:275368 6/19 (32%)
C2H2 Zn finger 537..557 CDD:275368 6/19 (32%)
C2H2 Zn finger 636..656 CDD:275368 6/19 (32%)
zf-C2H2_8 639..712 CDD:292531 28/96 (29%)
C2H2 Zn finger 666..688 CDD:275368 9/44 (20%)
zf-C2H2 694..716 CDD:278523 10/21 (48%)
C2H2 Zn finger 696..716 CDD:275368 9/19 (47%)
zf-H2C2_2 708..733 CDD:290200 9/24 (38%)
C2H2 Zn finger 724..744 CDD:275368 7/20 (35%)
Zfp652NP_001073676.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 60..234 31/188 (16%)
C2H2 Zn finger 246..265 CDD:275368 7/18 (39%)
C2H2 Zn finger 273..292 CDD:275368 5/18 (28%)
C2H2 Zn finger 300..320 CDD:275368 6/31 (19%)
C2H2 Zn finger 330..350 CDD:275368 4/19 (21%)
C2H2 Zn finger 358..378 CDD:275368 6/19 (32%)
SFP1 <380..463 CDD:227516 23/82 (28%)
C2H2 Zn finger 386..406 CDD:275368 3/19 (16%)
C2H2 Zn finger 414..434 CDD:275368 6/19 (32%)
COG5048 438..>487 CDD:227381 18/48 (38%)
C2H2 Zn finger 442..462 CDD:275368 9/19 (47%)
C2H2 Zn finger 470..486 CDD:275368 5/15 (33%)
Mediates interaction with CBFA2T3. /evidence=ECO:0000250 497..608
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 540..589
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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