DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8944 and CG6654

DIOPT Version :9

Sequence 1:NP_573065.1 Gene:CG8944 / 32517 FlyBaseID:FBgn0030680 Length:762 Species:Drosophila melanogaster
Sequence 2:NP_650429.1 Gene:CG6654 / 41831 FlyBaseID:FBgn0038301 Length:639 Species:Drosophila melanogaster


Alignment Length:567 Identity:122/567 - (21%)
Similarity:184/567 - (32%) Gaps:184/567 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   299 NISLAKDAIT--RKWDNLRTVYKRECNRMALEKTNI------STLWYFKELHF--LNEVYSYNDK 353
            |.||.|..|:  ..::....|:..|.....:|||..      ..|...||:.|  .|.:|..:|.
  Fly   132 NTSLIKSTISVDLDYEGEGEVFDYELPDEPVEKTTSLILQVQGNLKDEKEVVFTQTNVIYEGDDH 196

  Fly   354 MSDAVVKETSYRRRFSAIWNDT--------------STAKLLSMVKRYQCFYNRFDPDYRSKERR 404
            ..:..::|.:. ..|..:.|:.              |.||||:..:.     ::......|||..
  Fly   197 ELEQQIRECNL-AIFEGVDNEAEIITVTAPQVTTRKSAAKLLTQQEN-----DKHQTPVGSKEEA 255

  Fly   405 GEGLHQMAIELQQLIDVTTIQISKRISQLRFDYSKQ--------------KMERLNSER------ 449
            .|      :|.:|:     .|.:||.|:.| ...||              |..||.::|      
  Fly   256 RE------LEKEQV-----PQSAKRTSRRR-GVVKQDVPATPPSDAEPSPKQHRLGTQRKLSAPR 308

  Fly   450 ---------------------------------------------LGKKFIANYLYYDQMHFMDD 469
                                                         :.:.:..|..  :::....|
  Fly   309 AGTVNGPSTTSGAATTPELKYHCDRCNAGFAVEKSLMIHRRQKGCINRNYKCNEC--EKVFVSPD 371

  Fly   470 DIPPFKCAH----CPEI---VQTLRELDLHMLT-HQPSLGGGYYCNICSIQFHNAQEFDNHKQLH 526
            .:...:.:|    |||.   ..:...|..||:. |:.:|..  .||||...|.......:|.::|
  Fly   372 HLAEHQASHGAHNCPECGIRCDSKEALSKHMVQGHKRNLRN--QCNICQKVFTMLSTLRDHMRIH 434

  Fly   527 LGGVTEIKFNCELCTASFREKANYDEHLRRHNEELFLPSLALNHSIMEGGLGDDEIGVEGEESRG 591
            .|   |..|.|.:|..||.:.||..:|..||:|..........||.:.                 
  Fly   435 TG---EKPFVCNICGKSFTQNANLRQHKLRHSETKSFKCELCPHSFVT----------------- 479

  Fly   592 SGSRRKRRHAAKATDDMVDDDDRIGGGGGGGSGGGGTDIAKPYGCDVCRRSFATPGHLNAHRIVH 656
              ......||...|.|                        ||:.|:||...|.|...|..|:..|
  Fly   480 --KAELTSHARTHTGD------------------------KPFECEVCLARFTTSCSLAKHKRKH 518

  Fly   657 QDERERCYKCDYPQCNKSFVARNSLFEHLKQHYSNEEFKCDICGKTFKSTKNLQNHKQIHDKIKR 721
            ..||.  |.||.  |...|.|.|.|..|.:.|.....:.|..|.|||....:.|.|::.|...:.
  Fly   519 TGERP--YACDL--CPMRFTALNVLKNHRRTHTGERPYVCPFCSKTFTQRGDCQMHQRTHQGERI 579

  Fly   722 YVCQICGSAF-------AQAAGLYLHKRR-------HNRPNGAVGAV 754
            |:|.:|...|       :..||...|.:|       .|:.||: ||:
  Fly   580 YICPVCNEEFKSMPEMRSHLAGHEQHDKRLVHFTFLSNKENGS-GAL 625

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8944NP_573065.1 MADF_DNA_bdg 259..344 CDD:287510 14/54 (26%)
MADF 379..472 CDD:214738 22/157 (14%)
C2H2 Zn finger 476..496 CDD:275368 7/27 (26%)
C2H2 Zn finger 506..526 CDD:275368 6/19 (32%)
C2H2 Zn finger 537..557 CDD:275368 7/19 (37%)
C2H2 Zn finger 636..656 CDD:275368 7/19 (37%)
zf-C2H2_8 639..712 CDD:292531 24/72 (33%)
C2H2 Zn finger 666..688 CDD:275368 8/21 (38%)
zf-C2H2 694..716 CDD:278523 7/21 (33%)
C2H2 Zn finger 696..716 CDD:275368 7/19 (37%)
zf-H2C2_2 708..733 CDD:290200 7/31 (23%)
C2H2 Zn finger 724..744 CDD:275368 7/33 (21%)
CG6654NP_650429.1 zf-AD 6..79 CDD:285071
C2H2 Zn finger 331..354 CDD:275368 0/22 (0%)
COG5048 <357..570 CDD:227381 65/266 (24%)
C2H2 Zn finger 360..380 CDD:275368 2/21 (10%)
C2H2 Zn finger 385..406 CDD:275370 6/20 (30%)
C2H2 Zn finger 414..434 CDD:275368 6/19 (32%)
zf-H2C2_2 427..451 CDD:290200 9/26 (35%)
C2H2 Zn finger 442..490 CDD:275368 14/66 (21%)
C2H2 Zn finger 470..487 CDD:275368 2/35 (6%)
zf-H2C2_2 482..507 CDD:290200 10/48 (21%)
C2H2 Zn finger 498..518 CDD:275368 7/19 (37%)
zf-H2C2_2 510..534 CDD:290200 9/27 (33%)
C2H2 Zn finger 526..546 CDD:275368 8/21 (38%)
zf-H2C2_2 539..563 CDD:290200 8/23 (35%)
C2H2 Zn finger 554..574 CDD:275368 7/19 (37%)
C2H2 Zn finger 582..602 CDD:275368 4/19 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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