DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8944 and CG17359

DIOPT Version :9

Sequence 1:	NP_573065.1	Gene:	CG8944 / 32517	FlyBaseID:	FBgn0030680	Length:	762	Species:	Drosophila melanogaster
Sequence 2:	NP_648679.1	Gene:	CG17359 / 39549	FlyBaseID:	FBgn0036396	Length:	339	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	75/327 - (22%)
Similarity:	111/327 - (33%)	Gaps:	99/327 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   480 PEIVQTLRELDLHMLTHQPSLGGGYYCNICSIQFHNAQEFDNHKQLHLGGVTEIKFNCELCTASF 544
            |.:...|||                 |:.||:          ||:   .|:.:  |.|..|..:.
  Fly    36 PVLATMLRE-----------------CSGCSV----------HKE---DGMPQ--FICVECAEAV 68

  Fly   545 ----------REKANYDEHLRRHNEELFLPSLALN----------HSIMEGG------------- 576
                      |:...|.|.||...:||......||          .|:||.|
  Fly    69 RNAYRLRRQCRKSHQYFEQLRLMMKELDDIEYCLNIGDNIEPQMPVSVMEAGKTPETSEPLLVEL 133

  Fly   577 ----------------LGDD---EIGVEGEESRGSGSRRKRRHAAKATDDM--------VDDDDR 614
                            |.|:   ::......::...::.|||..:.:.:|.        .:|||:
  Fly   134 VQVKYMPPEPKPISSPLPDNNEHKLAQSYSPAKTPHNKSKRRARSYSDNDSWSPDSELEHEDDDK 198

  Fly   615 IGGGGGGGSGGGGTDIAKPYGCDVCRRSFATPGHLNAHRIVHQDERERCYKCDYPQCNKSFVARN 679
            |   ......|....:..||.|.:|.:||....:|..|..:|..||.  |||..  |.:||..:.
  Fly   199 I---WNASKRGKPKRVPGPYRCKLCTQSFTQKQNLEIHMRIHTGERP--YKCSL--CPRSFAQKG 256

  Fly   680 SLFEHLKQHYSNEEFKCDICGKTFKSTKNLQNHKQIHDKIKRYVCQICGSAFAQAAGLYLHKRRH 744
            :|..|.:.|.....|.|..|.|.|:....||.|.:.|...:.:.|..|..:|.|..||..|...|
  Fly   257 NLQSHTRCHTGERPFGCPNCPKRFRQVGQLQVHTRTHTGEQPFKCSKCQQSFKQLNGLQKHMSAH 321

  Fly   745 NR 746
            .|
  Fly   322 TR 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8944	NP_573065.1	MADF_DNA_bdg	259..344	CDD:287510
		MADF	379..472	CDD:214738
		C2H2 Zn finger	476..496	CDD:275368	4/15 (27%)
		C2H2 Zn finger	506..526	CDD:275368	5/19 (26%)
		C2H2 Zn finger	537..557	CDD:275368	7/29 (24%)
		C2H2 Zn finger	636..656	CDD:275368	6/19 (32%)
		zf-C2H2_8	639..712	CDD:292531	24/72 (33%)
		C2H2 Zn finger	666..688	CDD:275368	6/21 (29%)
		zf-C2H2	694..716	CDD:278523	8/21 (38%)
		C2H2 Zn finger	696..716	CDD:275368	7/19 (37%)
		zf-H2C2_2	708..733	CDD:290200	7/24 (29%)
		C2H2 Zn finger	724..744	CDD:275368	7/19 (37%)
CG17359	NP_648679.1	zf-AD	6..88	CDD:285071	16/83 (19%)
		zf-C2H2	215..237	CDD:278523	7/21 (33%)
		C2H2 Zn finger	217..237	CDD:275368	6/19 (32%)
		zf-H2C2_2	229..254	CDD:290200	11/28 (39%)
		C2H2 Zn finger	245..265	CDD:275368	6/21 (29%)
		zf-H2C2_2	257..282	CDD:290200	8/24 (33%)
		C2H2 Zn finger	273..293	CDD:275368	7/19 (37%)
		zf-H2C2_2	286..310	CDD:290200	7/23 (30%)
		C2H2 Zn finger	301..321	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100