DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8944 and CG10654

DIOPT Version :9

Sequence 1:	NP_573065.1	Gene:	CG8944 / 32517	FlyBaseID:	FBgn0030680	Length:	762	Species:	Drosophila melanogaster
Sequence 2:	NP_001261767.1	Gene:	CG10654 / 39428	FlyBaseID:	FBgn0036294	Length:	412	Species:	Drosophila melanogaster

Alignment Length:	323	Identity:	70/323 - (21%)
Similarity:	119/323 - (36%)	Gaps:	92/323 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   470 DIPP---FK--CAHCPEIVQTLREL---------DLHMLTHQPSLGGGYYCNICSIQFHNAQEFD 520
            |:||   .|  |..|.::||...:.         :...|.....:|    |:  .::.|...:.|
  Fly    77 DLPPQLVLKSICECCYQLVQKFHDFQRMCAESLRNFEKLLQDIDIG----CH--KLEDHTWHDLD 135

  Fly   521 NHKQLHLGGVTEIKFNCELCTASFREKANYDEHLRRHNEELFLPSLALNHSIMEGGLGDDEIGVE 585
            ...:.:.....|.:.:.. |.|:.:|..::..      .::.||...:...|..|...::|:.|.
  Fly   136 TPSESNESTNPEAQSHAP-CIAATQEIVSFIW------PQVCLPLAVILSRITLGASLEEEVYVI 193

  Fly   586 GEESR----------------GSGSRRKRRHAAKATDDMVDDDDRIGGGGGGGSGGGGTDIAKPY 634
            .:||.                |:..||..||..:
  Fly   194 EDESAKQDLGQEKLSISSKLLGARKRRGVRHTLE------------------------------- 227

  Fly   635 GCDVCRRSFATPGHLNAHRIVHQDERERCYKCDYPQCNKSFVARNSLFEHLKQHYSNEE-----F 694
             |.:|.|.|..|..|.||  :.|.|..|.|.|.:  |.||:...|.|..||:|.::|.:     :
  Fly   228 -CRICHRGFYKPSLLEAH--MQQHEGLRPYTCVH--CAKSYARANLLESHLRQMHNNADAARIIY 287

  Fly   695 KCDICGKTFKSTKNLQNH-KQIHDKI-------KRYVCQICGSAFAQAAGLYLHKRRHNRPNG 749
            .|..|.|.:.:.::|:.| ::.|::.       .|::|:.||..||:.|.|..||..|....|
  Fly   288 ACPSCNKVYTANRSLKYHMRRTHERYHESESPDARHICEECGKCFARKAHLTRHKMVHGSVEG 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8944	NP_573065.1	MADF_DNA_bdg	259..344	CDD:287510
		MADF	379..472	CDD:214738	1/1 (100%)
		C2H2 Zn finger	476..496	CDD:275368	5/28 (18%)
		C2H2 Zn finger	506..526	CDD:275368	3/19 (16%)
		C2H2 Zn finger	537..557	CDD:275368	3/19 (16%)
		C2H2 Zn finger	636..656	CDD:275368	8/19 (42%)
		zf-C2H2_8	639..712	CDD:292531	25/77 (32%)
		C2H2 Zn finger	666..688	CDD:275368	8/21 (38%)
		zf-C2H2	694..716	CDD:278523	5/22 (23%)
		C2H2 Zn finger	696..716	CDD:275368	5/20 (25%)
		zf-H2C2_2	708..733	CDD:290200	8/32 (25%)
		C2H2 Zn finger	724..744	CDD:275368	9/19 (47%)
CG10654	NP_001261767.1	zf-AD	39..115	CDD:285071	8/37 (22%)
		C2H2 Zn finger	228..248	CDD:275368	8/21 (38%)
		C2H2 Zn finger	256..313	CDD:275368	16/58 (28%)
		C2H2 Zn finger	289..314	CDD:275368	6/24 (25%)
		zf-C2H2	323..345	CDD:278523	9/21 (43%)
		C2H2 Zn finger	325..345	CDD:275368	9/19 (47%)
		C2H2 Zn finger	355..376	CDD:275368
		C2H2 Zn finger	385..405	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455468
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930