DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8944 and CG12219

DIOPT Version :9

Sequence 1:NP_573065.1 Gene:CG8944 / 32517 FlyBaseID:FBgn0030680 Length:762 Species:Drosophila melanogaster
Sequence 2:NP_572312.1 Gene:CG12219 / 31572 FlyBaseID:FBgn0043796 Length:562 Species:Drosophila melanogaster


Alignment Length:526 Identity:81/526 - (15%)
Similarity:133/526 - (25%) Gaps:267/526 - (50%)


- Green bases have known domain annotations that are detailed below.


  Fly   421 VTTIQISKRISQLRFDYSKQKMERLNSERLGKKFIANYLYYD-QMHFMDD------DIPP---FK 475
            ::|...::..|||...::..|:..|....|..:|:|    .| .:::.:|      |..|   .:
  Fly    62 ISTCICTECCSQLESFHNFWKLVELKQTTLCSQFLA----IDCDVNWSEDGSETQLDAQPQLLLE 122

  Fly   476 CAHCPEIVQTLRELDLHMLTHQPSLGGGYYCNICSIQFHNAQEFDNHKQLHLGGVTEIKFNCELC 540
            .|..|::|             .|:....:.|..|...|...:..:.|...|.|   :....|..|
  Fly   123 PAEEPKVV-------------TPTTANKFPCMFCEKSFKMRRYLEEHIATHTG---DRPIACPYC 171

  Fly   541 TASFREKANYDEHLRRHNEELFL------------------------------------------ 563
            ..:||.::|...|::..:...:|                                          
  Fly   172 EMAFRCRSNMYTHVKSKHTTQWLKAREERDAAKSNQNHTTPEETAPAVLVPVPAPAPALASAPAS 236

  Fly   564 ------------------------------------------------PSLALNHSIMEGGLGDD 580
                                                            ||.|:|.:|.:      
  Fly   237 SASPGNTVNPAATATPASSATPTTNLAAAPLPSPPTVQQLPLSVIKSQPSEAMNLTITK------ 295

  Fly   581 EIGVEGEESRGSGSRRKRR--HAAKAT-----DDMVDDDD------------------------- 613
               .....||||.:|..||  |:.|..     .|:.|:|.                         
  Fly   296 ---TPPSGSRGSRNRSSRRKTHSPKKVQHTEGSDVSDEDSPQKRLKENELILANYNAVAAAVVAA 357

  Fly   614 -RIGGGGGG------------------------------------GSGGG--------GTDIAKP 633
             .:.|...|                                    |:...        ||.:|.|
  Fly   358 ASLTGNPPGQPDSLQQRLCASLLQQQHQEQLFAVMSATAAAAAAVGTSSATTTTTTTTGTMMAHP 422

  Fly   634 YG------------------------CDVCRRSFATPGHLNAHRIVHQDERERCYKCDYPQCNKS 674
            ||                        ..:|......||           :..||           
  Fly   423 YGNHPPSETDKRPAAPLQAVIHAAPVSIICPNCGELPG-----------QNHRC----------- 465

  Fly   675 FVARNSLFEHLKQHYSNEEFKCDICGKTFKSTKNLQNHKQIHDKIKRYVCQICGSAFAQAAGLYL 739
                          .|..::.||:|||:||..:.|:.|...|..:|.:.|..|.:.|...:.:|.
  Fly   466 --------------LSKPKYACDVCGKSFKMKRYLEEHFATHTGVKLHTCAFCPTEFRSKSNMYH 516

  Fly   740 H-KRRH 744
            | ||:|
  Fly   517 HTKRKH 522

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8944NP_573065.1 MADF_DNA_bdg 259..344 CDD:287510
MADF 379..472 CDD:214738 12/57 (21%)
C2H2 Zn finger 476..496 CDD:275368 3/19 (16%)
C2H2 Zn finger 506..526 CDD:275368 4/19 (21%)
C2H2 Zn finger 537..557 CDD:275368 6/19 (32%)
C2H2 Zn finger 636..656 CDD:275368 3/19 (16%)
zf-C2H2_8 639..712 CDD:292531 14/72 (19%)
C2H2 Zn finger 666..688 CDD:275368 0/21 (0%)
zf-C2H2 694..716 CDD:278523 9/21 (43%)
C2H2 Zn finger 696..716 CDD:275368 9/19 (47%)
zf-H2C2_2 708..733 CDD:290200 7/24 (29%)
C2H2 Zn finger 724..744 CDD:275368 7/20 (35%)
CG12219NP_572312.1 zf-AD 2..94 CDD:285071 7/31 (23%)
C2H2 Zn finger 140..160 CDD:275368 4/19 (21%)
COG4049 149..204 CDD:226535 10/57 (18%)
C2H2 Zn finger 168..186 CDD:275368 6/17 (35%)
C2H2 Zn finger 473..493 CDD:275370 9/19 (47%)
C2H2 Zn finger 501..522 CDD:275370 7/20 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45455478
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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