DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG8944 and Zfp160

DIOPT Version :10

Sequence 1:NP_573065.1 Gene:CG8944 / 32517 FlyBaseID:FBgn0030680 Length:762 Species:Drosophila melanogaster
Sequence 2:NP_663458.2 Gene:Zfp160 / 224585 MGIID:108187 Length:650 Species:Mus musculus


Alignment Length:471 Identity:105/471 - (22%)
Similarity:170/471 - (36%) Gaps:133/471 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   320 RECNRMALEKTNISTLWYFKELHFLNEVYSYNDKMSDAVVKETSYRRRFSAIWNDTSTAKLLSMV 384
            :||:::.   :..|:|.|.:::|...::|...:      ..:..:||.:..:.....|.     .
Mouse   149 KECDKVF---SYTSSLAYHRQIHTGEKLYKCLE------CGKAFFRRSYLLVHERHHTG-----A 199

  Fly   385 KRYQCFYNRFDPDYRSKERRGEGLHQMAIELQQLIDVTTIQISKRISQLRFDYSKQKMERLNSER 449
            |.|:|            ...|:...|                :..:...|..::.:|..:.|  .
Mouse   200 KPYKC------------NECGKVFSQ----------------NSHLKSHRRIHTGEKPFKCN--H 234

  Fly   450 LGKKFI--ANYLYYDQMHFMDDDIPPFKCAHCPEIVQTLRELDLHMLTH---QPSLGGGYYCNIC 509
            .||.|.  :|..::..:|..|   .|:||..|.::......|.:|..||   :|     |.||.|
Mouse   235 CGKAFSVRSNLTHHQVIHTGD---KPYKCNECGKVFSQTSSLTIHRRTHTGEKP-----YRCNEC 291

  Fly   510 SIQFHNAQEFDNHKQLHLGGVTEIKFNCELCTASFREKANYDEHLRRHNEE------------LF 562
            ...|.:....:.|:.:|.|   |..:.|..|...|.:.::...|.|.|..|            ..
Mouse   292 GKVFSSHSNLNTHQAIHTG---EKPYKCSECGKVFTQNSHLANHWRIHTGEKPYKCNECGKAFSV 353

  Fly   563 LPSLALNHSIMEG-----------------------GLGDDEIGVEGEE-----SRGSG-SRRKR 598
            ..||..:.:|..|                       |:...|...:.||     |:.|. :|..|
Mouse   354 YSSLTTHQAIHTGEKPYKCNECGKVFTQNSHLASHRGVHSGEKPYKCEECGKLFSQTSNLARHWR 418

  Fly   599 RHAAKATDDMVDDDDRIGGGGGGGSGGGGTDIAKPYGCDVCRRSFATPGHLNAHRIVHQDERERC 663
            .|..:                            |||.|..|.::|:....|.||:::|..|:.  
Mouse   419 VHTGE----------------------------KPYKCSECGKAFSVRSSLIAHQVIHTGEKP-- 453

  Fly   664 YKCDYPQCNKSFVARNSLFEHLKQHYSNEEFKCDICGKTFKSTKNLQNHKQIHDKIKRYVCQICG 728
            |||  .:|.|.|...:||..|.:.|...:.::|:.|||.|.|..||..|:.||...|.|.|..||
Mouse   454 YKC--TECGKVFSQTSSLSIHQRIHTGEKPYRCNECGKAFNSHSNLNTHQVIHTGQKPYKCMQCG 516

  Fly   729 SAFAQAAGLYLHKRRH 744
            ..|.|.:.|..|:|.|
Mouse   517 KVFTQNSHLANHQRTH 532

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG8944NP_573065.1 MADF_DNA_bdg 259..344 CDD:463144 6/23 (26%)
MADF 379..472 CDD:214738 14/94 (15%)
C2H2 Zn finger 476..496 CDD:275368 4/19 (21%)
C2H2 Zn finger 506..526 CDD:275368 5/19 (26%)
C2H2 Zn finger 537..557 CDD:275368 5/19 (26%)
C2H2 Zn finger 636..656 CDD:275368 6/19 (32%)
COG5048 <666..734 CDD:227381 25/67 (37%)
C2H2 Zn finger 666..688 CDD:275368 7/21 (33%)
C2H2 Zn finger 696..716 CDD:275368 9/19 (47%)
C2H2 Zn finger 724..744 CDD:275368 8/19 (42%)
Zfp160NP_663458.2 KRAB 8..68 CDD:214630
C2H2 Zn finger 148..168 CDD:275368 5/21 (24%)
C2H2 Zn finger 176..196 CDD:275368 2/25 (8%)
COG5048 200..635 CDD:227381 95/406 (23%)
C2H2 Zn finger 204..224 CDD:275368 4/47 (9%)
C2H2 Zn finger 232..252 CDD:275368 5/21 (24%)
C2H2 Zn finger 260..280 CDD:275368 4/19 (21%)
C2H2 Zn finger 288..308 CDD:275368 5/19 (26%)
C2H2 Zn finger 316..336 CDD:275368 5/19 (26%)
C2H2 Zn finger 344..364 CDD:275368 2/19 (11%)
C2H2 Zn finger 372..392 CDD:275368 1/19 (5%)
C2H2 Zn finger 400..420 CDD:275368 6/19 (32%)
C2H2 Zn finger 428..448 CDD:275368 6/19 (32%)
C2H2 Zn finger 456..476 CDD:275368 7/21 (33%)
C2H2 Zn finger 484..504 CDD:275368 9/19 (47%)
C2H2 Zn finger 512..532 CDD:275368 8/19 (42%)
C2H2 Zn finger 540..560 CDD:275368
C2H2 Zn finger 568..588 CDD:275368
C2H2 Zn finger 596..616 CDD:275368
C2H2 Zn finger 624..644 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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