Protein Alignment Arp6 and ACTL6A

DIOPT Version :10

• Sequence 1: NP_511165.1
• Gene: Arp6 / 32514
• FlyBaseID: FBgn0011741
• Length: 398
• Species: Drosophila melanogaster
• Sequence 2: NP_004292.1
• Gene: ACTL6A / 86
• HGNCID: 24124
• Length: 429
• Species: Homo sapiens
• Alignment Length: 437
• Identity: 94/437 - (21%)
• Similarity: 187/437 - (42%)
• Gaps: 67/437 - (15%)

  Fly     6 VVLDNGAHTAKVGLANQDEPHV-VPNCI-MKAKSERRRAFVGNQIDECRDTSALYY--------- 59
            :|.|.|::|.:.|.|.:|.|.| .|..| |..:.:.....:....|:.:.....||
Human    14 LVFDIGSYTVRAGYAGEDCPKVDFPTAIGMVVERDDGSTLMEIDGDKGKQGGPTYYIDTNALRVP 78

  Fly    60 ------ILAFQRGYLLNWHTQKTVWDYIFSKDGIGCSLENRNIVITEPQMNFQSIQEATLEILFE 118
                  |...:.|.:.:|.:.:.:.|:.: |..:........::::|...|.::.:|...|::||
Human    79 RENMEAISPLKNGMVEDWDSFQAILDHTY-KMHVKSEASLHPVLMSEAPWNTRAKREKLTELMFE 142

  Fly   119 EYKVDGVYKTTAADLAAFNYVADSEERTTMESLNCIIIDVGYSFTHVVPFVLGRRVLQGIRRIDM 183
            .|.:...:....|.|.||     :..|:|     .:|:|.|.:.|..:|...|..:.|||.:..:
Human   143 HYNIPAFFLCKTAVLTAF-----ANGRST-----GLILDSGATHTTAIPVHDGYVLQQGIVKSPL 197

  Fly   184 GGKALTNQLKELISYRHLNVMDESHVVNQIKEDVCFVAEDFKQAMQVHYS-EEKRREVTVDY--- 244
            .|..:|.|.:||....::.::....:.::         |..::....::. :||..:||..:
Human   198 AGDFITMQCRELFQEMNIELVPPYMIASK---------EAVREGSPANWKRKEKLPQVTRSWHNY 253

  Fly   245 ----VLPDFTTVKRGYVRVPGKPREDEEQQQMVSL---------CN---ERFTVPELLFNPSDI- 292
                |:.||   :...::|.....:::...||.::         |:   ||..:||.||:||::
Human   254 MCNCVIQDF---QASVLQVSDSTYDEQVAAQMPTVHYEFPNGYNCDFGAERLKIPEGLFDPSNVK 315

  Fly   293 ---GVQQVGIPEAVADCLKACPWEAHRELLLNILIVGGSAQFPGFLPRLKRDLRALVPDDLEVSL 354
               |...:|:...|...:..|..:....|..::::.||:.....|..||.|:|....|..:.:.|
Human   316 GLSGNTMLGVSHVVTTSVGMCDIDIRPGLYGSVIVAGGNTLIQSFTDRLNRELSQKTPPSMRLKL 380

  Fly   355 ICPEDPV--RY-AWYGGKEVATSPNFEEFVYTQDDYEEYGFQGINQR 398
            |.....|  |: :|.||..:|:...|::...::.:|||.|.|.:.::
Human   381 IANNTTVERRFSSWIGGSILASLGTFQQMWISKQEYEEGGKQCVERK 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arp6	NP_511165.1	ASKHA_NBD_Arp6	5..391	CDD:466816	92/428 (21%)
ACTL6A	NP_004292.1	ASKHA_NBD_Arp4_ACTL6-like	8..420	CDD:466846	92/428 (21%)